Patents by Inventor Luk Vandenberghe

Luk Vandenberghe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of increasing the function of an AAV vector
    Patent number: 8999678
    Abstract: A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: April 7, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Luk Vandenberghe, Guangping Gao, James M. Wilson
  • Method of Increasing the Function of an AAV Vector
    Publication number: 20090197338
    Abstract: A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.
    Type: Application
    Filed: April 7, 2006
    Publication date: August 6, 2009
    Applicant: The Trustees of teh University of Pennsylvania
    Inventors: Luk Vandenberghe, Guangping Gao, James M. Wilson