Patents by Inventor Lukas Drasar

Lukas Drasar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipopolyamines of spermine type for construction of liposomal transfection systems
    Patent number: 9393200
    Abstract: The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C—N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy-alkylcarboxamide linker or ?-hydroxyalkylcarboxamidopolyethyleneglycol-carboxamide linker, and wherein a hydrophobic domain Y is an acyl symmetrically branched in the position C(2) or cholesteryl. The invention further provides a method of preparation of said lipopolyamines and their use for construction of polycationic liposomal drug carriers.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: July 19, 2016
    Assignees: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., VYZKUMNY USTAV VETERINARNIHO LEKARSTVI, V.V.I.
    Inventors: Lukas Drasar, Miroslav Ledvina, Zina Korvasova, Jaroslav Turanek
  • LIPOPOLYAMINES OF SPERMINE TYPE FOR CONSTRUCTION OF LIPOSOMAL TRANSFECTION SYSTEMS
    Publication number: 20150018436
    Abstract: The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C—N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy-alkylcarboxamide linker or ?-hydroxyalkylcarboxamidopolyethyleneglycol-carboxamide linker, and wherein a hydrophobic domain Y is an acyl symmetrically branched in the position C(2) or cholesteryl. The invention further provides a method of preparation of said lipopolyamines and their use for construction of polycationic liposomal drug carriers.
    Type: Application
    Filed: January 14, 2013
    Publication date: January 15, 2015
    Applicants: VYZKUMNY USTAV VETERINARNIHO LEKARSTVI, V.V.I., USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I.
    Inventors: Lukas Drasar, Miroslav Ledvina, Zina Korvasova, Jaroslav Turanek