Patents by Inventor Lukas Paul
Lukas Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11947913Abstract: Techniques for performing multi-stage entity resolution (ER) processing are described. A system may determine a portion of a user input corresponding to an entity name, and may request an entity provider component to perform a search to determine one or more entities corresponding to the entity name. The preliminary search results may be sent to a skill selection component for processing, while the entity provider component performs a complete search to determine entities corresponding to the entity name. A selected skill component may request the complete search results to perform its processing, including determining an output responsive to the user input.Type: GrantFiled: June 24, 2021Date of Patent: April 2, 2024Assignee: Amazon Technologies, Inc.Inventors: David Paul Ramos, Tonytip Ketudat, Vikas Chawla, Lukas Leon Brower
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Patent number: 10538795Abstract: The present invention relates to methods for generating a labelled nucleic acid from an RNA comprising a 5? protecting group, said method comprises the steps of obtaining a mixture of template strands of nucleic acids, said mixture comprising said RNA and further potentially other nucleic acids without a 5? protecting group, annealing at least one oligonucleotide primer to the template strand of said RNA and potentially other nucleic acids, and template sequence dependent extending said primer, thereby obtaining a complementary nucleic acid strand annealed to its template strand, or providing the RNA in duplex with a complementary nucleic acid strand annealed to its template strand, and optionally modifying the extension product of said nucleic acids without 5? protecting group either on the 5? end of the template strand or on the 3? end of the complementary strand, or both, and labelling a complementary nucleic acid of a double stranded nucleic acid not modified, wherein therefore the labelled nucleic acid dType: GrantFiled: July 10, 2013Date of Patent: January 21, 2020Assignee: LEXOGEN GMBHInventors: Alexander Seitz, Irmlind Gabler, Lukas Paul
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Patent number: 10513726Abstract: The present invention relates to the field of transcriptomics and provides a method for the controlled identification and/or quantification of transcript variants in samples, comprising providing a reference set of artificial polynucleic acid molecules simulating transcript variants and adding said reference set as external control to samples comprising transcript variants. The present invention further provides such a reference set, as well as a method to produce such a reference set.Type: GrantFiled: July 9, 2015Date of Patent: December 24, 2019Assignee: LEXOGEN GMBHInventors: Lukas Paul, Petra Kubala, Torsten Reda
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Publication number: 20170321248Abstract: The present invention relates to the field of transcriptomics and provides a method for the controlled identification and/or quantification of transcript variants in samples, comprising providing a reference set of artificial polynucleic acid molecules simulating transcript variants and adding said reference set as external control to samples comprising transcript variants. The present invention further provides such a reference set, as well as a method to produce such a reference set.Type: ApplicationFiled: July 9, 2015Publication date: November 9, 2017Applicant: LEXOGEN GMBHInventors: Lukas Paul, Petra Kubala, Torsten Reda
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Publication number: 20150147785Abstract: The present invention relates to methods for generating a labelled nucleic acid from an RNA comprising a 5? protecting group, said method comprises the steps of obtaining a mixture of template strands of nucleic acids, said mixture comprising said RNA and further potentially other nucleic acids without a 5? protecting group, annealing at least one oligonucleotide primer to the template strand of said RNA and potentially other nucleic acids, and template sequence dependent extending said primer, thereby obtaining a complementary nucleic acid strand annealed to its template strand, or providing the RNA in duplex with a complementary nucleic acid strand annealed to its template strand, and optionally modifying the extension product of said nucleic acids without 5? protecting group either on the 5? end of the template strand or on the 3? end of the complementary strand, or both, and labelling a complementary nucleic acid of a double stranded nucleic acid not modified, wherein therefore the labelled nucleic acid dType: ApplicationFiled: July 10, 2013Publication date: May 28, 2015Inventors: Alexander Seitz, Irmlind Gabler, Lukas Paul
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Publication number: 20120238457Abstract: The present invention relates to a method of ordering nucleic acid molecule fragment sequences derived from a pool of potentially diverse RNA molecules comprising optionally reverse transcribing the RNA molecules to provide a pool of cDNA molecules, segregating nucleic acids from said template RNA or cDNA pool, selecting for potentially different templates with a distinctive nucleic acid feature shared by the segregated templates, thereby providing at least a first subpool of nucleic acids, optionally once or more further segregating nucleic acids from said template RNA or cDNA, selectively segregating nucleic acids with a different distinctive nucleic acid feature, thereby providing one or more further subpool(s) of nucleic acids, generating fragments of said segregated nucleic acid molecules by fragmenting or obtaining fragment copies of said segregated nucleic acid molecules, wherein the fragments of each subpool or combined subpools remain separable from fragments of other subpools or other combined suType: ApplicationFiled: December 10, 2010Publication date: September 20, 2012Applicant: LEXOGEN GMBHInventors: Alexander Seitz, Lukas Paul, Max Jan Van Min
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Patent number: 5754824Abstract: A general approach to the synthesis of logic array modules (LAMs) is used to implement a multilevel combinational acyclic network. The network consists of abstract gates, which perform primitive logic functions and nets to connect them. The inputs to the entire network are called the primary inputs and the outputs of the entire network are the primary outputs. The first step in the synthesis of the LAMs used to implement the network is to partition the network vertically to define a plurality of logic segments wherein each output of a logic segment can potentially be implemented in a single logic array module. The second step is to partition horizontally the plurality of logic segments to reduce the size of the segments to a size that can efficiently be implemented as a logic array module. A symbolic representation is generated in a logic array module table of an internal structure of the logic array module based on the horizontally partitioned logic segments.Type: GrantFiled: May 10, 1995Date of Patent: May 19, 1998Assignee: International Business Machines CorporationInventors: Robert Damiano, Ilan Yitshak Spillinger, Louise Helen Trevillyan, Lukas Paul Pieter Pepijn Van Ginneken