Patents by Inventor Lukas Spichal

Lukas Spichal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6, 9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions
    Publication number: 20110230503
    Abstract: Certain 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are provided. These 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for treating mammalian cells, and especially human skin cells, in order to ameliorate the adverse effects of aging, treat skin disease states, treat immunological responses resulting from or associated with inflammation, and the like.
    Type: Application
    Filed: May 26, 2011
    Publication date: September 22, 2011
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Jiri Voller, Karel Dolezal, Miroslav Strnad, Frank J. Massino
  • 6, 9-Disubstituted Purine Derivatives and Their Use for Treating Skin
    Publication number: 20110224238
    Abstract: The present invention provides methods and compositions for countering the adverse effects of aging on mammalian cells in vitro and in vivo, especially human skin cells and human skin, and treatment of hyperproliferative and related skin diseases in mammals by administering compositions containing 6,9-disubstituted purine derivatives.
    Type: Application
    Filed: May 26, 2011
    Publication date: September 15, 2011
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Ludek Frolich, Karel Dolezal, Miroslav Strnad, Frank J. Massino
  • 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions
    Patent number: 7960397
    Abstract: Certain 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts of the following general formula are provided wherein R6 and R9 are as defined in the specification. These 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for application to mammalian cells, and especially human skin cells, in order to improve the cosmetic appearance of the mammalian cells, especially human skin.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: June 14, 2011
    Assignee: Institute of Experimental Botany, Academy of Sciences of the Czech Republic
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Jiri Voller, Karel Dolezal, Miroslav Strnad, Frank J. Massino
  • Substituted 6-(alkylbenzylamino)purine derivatives for use as cytokinin receptor antagonists and preparations containing these derivatives
    Publication number: 20100240537
    Abstract: The invention relates to 6-(alkylbenzylamino)purine derivatives of the general formula I for use as cytokinin receptor antagonists, wherein R1 is selected from the group comprising hydroxyl, amino, nitro, thio and alkyl group, and R2 denotes one to four alkyl groups. The invention also relates to preparations containing these derivatives.
    Type: Application
    Filed: October 3, 2008
    Publication date: September 23, 2010
    Inventors: Lukas Spichal, Igor Popa, Jiri Voller, Karel Dolezal, Miroslav Strnad, Tomas Werner, Thomas Schmulling
  • 6,9-Disubstituted Purine Derivatives and Their Use For Treating Skin
    Publication number: 20100234401
    Abstract: The present invention provides methods and compositions for countering the adverse effects of aging on mammalian cells in vitro and in vivo, especially human skin cells and human skin, and treatment of hyperproliferative and related skin diseases in mammals by administering compositions containing 6,9-disubstituted purine derivatives.
    Type: Application
    Filed: May 24, 2010
    Publication date: September 16, 2010
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Ludek Frohlich, Karel Dolezal, Miroslav Strnad, Frank J. Massino
  • SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES
    Publication number: 20100190806
    Abstract: The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.
    Type: Application
    Filed: July 2, 2008
    Publication date: July 29, 2010
    Inventors: Lukas Spichal, Marketa Gemrotova, Marek Zatloukal, Jitka Frebortova, Petr Galuszka, Tomas Werner, Thomas Schmulling, Karel Dolezal, Miroslav Strnad
  • 6,9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions
    Publication number: 20090170879
    Abstract: Certain 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are provided. These 6,9-disubstituted purine derivatives and their pharmaceutically acceptable salts are useful in compositions for treating mammalian cells, and especially human skin cells, in order to ameliorate the adverse effects of aging, treat skin disease states, treat immunological responses resulting from or associated with inflammation, and the like.
    Type: Application
    Filed: December 28, 2007
    Publication date: July 2, 2009
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Jiri Voller, Karel Dolezal, Miroslav Strnad, Frank J. Massino
  • 6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin
    Publication number: 20080009508
    Abstract: The present invention provides methods and compositions for countering the adverse effects of aging on mammalian cells in vitro and in vivo, especially human skin cells and human skin, and treatment of hyperproliferative and related skin diseases in mammals by administering compositions containing 6,9-disubstituted purine derivatives.
    Type: Application
    Filed: July 9, 2007
    Publication date: January 10, 2008
    Inventors: Lucie Szucova, Marek Zatloukal, Lukas Spichal, Ludek Frohlich, Karel Dolezal, Miroslav Strnad, Frank J. Massino