Patents by Inventor Lukas STURMBERGER

Lukas STURMBERGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230257744
    Abstract: A promoter or variant thereof has increased relative expression efficiency, in particular a formate dehydrogenase promoter variant has increased relative expression efficiency, and a method provides for recombinant protein production and for increasing the relative expression efficiency of a nucleotide sequence having promoter activity.
    Type: Application
    Filed: June 9, 2021
    Publication date: August 17, 2023
    Applicant: DSM Austria GmbH
    Inventors: Florian KRAINER, Lukas STURMBERGER, Patricia MENCZIK
  • Patent number: 9822357
    Abstract: The invention refers to a library of bidirectional expression cassettes or expression vectors comprising a repertoire of bidirectional promoter sequences, each expression cassette comprising a promoter sequence operably linked to a first gene in one direction, and operably linked to an oppositely oriented second gene in the other direction which is different from the first gene, and bidirectional Pichia pastoris or CHO cells promoter sequences. The invention further refers to a method of screening or selecting a bidirectional promoter suitable for expressing at least two GOI in a host cell and a kit comprising a) an expression cassette consisting of the first and second genes and a stuffer sequence separating them, which stuffer sequence comprises a recognition site for a type IIS restriction enzyme at both ends; b) the type IIS restriction enzyme; c) and a repertoire of promoter, preferably a promoter library including bidirectional promoters.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: November 21, 2017
    Assignee: TECHNISCHE UNIVERSITAT GRAZ
    Inventors: Thomas Vogl, Thomas Kickenweiz, Lukas Sturmberger, Anton Glieder
  • Publication number: 20150011407
    Abstract: The invention refers to a library of bidirectional expression cassettes or expression vectors comprising a repertoire of bidirectional promoter sequences, each expression cassette comprising a promoter sequence operably linked to a first gene in one direction, and operably linked to an oppositely oriented second gene in the other direction which is different from the first gene, and bidirectional Pichia pastoris or CHO cells promoter sequences. The invention further refers to a method of screening or selecting a bidirectional promoter suitable for expressing at least two GOI in a host cell and a kit comprising a) an expression cassette consisting of the first and second genes and a stuffer sequence separating them, which stuffer sequence comprises a recognition site for a type IIS restriction enzyme at both ends; b) the type IIS restriction enzyme; c) and a repertoire of promoter, preferably a promoter library including bidirectional promoters.
    Type: Application
    Filed: July 7, 2014
    Publication date: January 8, 2015
    Inventors: Thomas VOGL, Thomas KICKENWEIZ, Lukas STURMBERGER, Anton GLIEDER