Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.

Abstract: A wellbore isolation system is disclosed. The wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore. The deflector includes a channel extending axially through the deflector, and a degradable plug disposed in the channel and engaged with the channel to prevent fluid flow through the channel.

Abstract: A main well bore is drilled. The main well bore is completed and stimulated. The main well bore is sealed. A lateral well bore is drilled off the main well bore. A junction that allows communication with the lateral well bore and that connects the main well bore is inserted. The lateral well bore is stimulated through the junction. The main well bore is unsealed, allowing comingled flow from the main bore and the lateral bore.

Abstract: Methods and apparatus for milling a window for a lateral wellbore in a casing string. An example method introduces a milling assembly into a primary wellbore, the milling assembly comprising: a whipstock, a guide bar coupled to the whipstock, and a wash pipe coupled to the guide bar. The method further includes running the milling assembly to a depth at which it is adjacent to the window in the casing string; securing the whipstock in the casing string; decoupling the wash pipe from the guide bar; guiding the wash pipe to mill the guide bar without milling the whipstock; and milling the window in the casing string with the wash pipe.

Abstract: Methods and apparatus for milling a window for a lateral wellbore in a casing string. An example method introduces a milling assembly into a primary wellbore, the milling assembly comprising: a whipstock, a guide bar coupled to the whipstock, and a wash pipe coupled to the guide bar. The method further includes running the milling assembly to a depth at which it is adjacent to the window in the casing string; securing the whipstock in the casing string; decoupling the wash pipe from the guide bar; guiding the wash pipe to mill the guide bar without milling the whipstock; and milling the window in the casing string with the wash pipe.

Abstract: A main well bore is drilled. The main well bore is completed and stimulated. The main well bore is sealed. A lateral well bore is drilled off the main well bore. A junction that allows communication with the lateral well bore and that connects the main well bore is inserted. The lateral well bore is stimulated through the junction. The main well bore is unsealed, allowing comingled flow from the main bore and the lateral bore.

Abstract: Some embodiments facilitate remote monitoring of an activity at one or more facilities by a vehicle. Data is received at a communications interface from a remote device that is co-located with the vehicle. The data includes a vehicle identifier and a vehicle location indicator. A zone data record is accessed. The zone data record includes a plurality of zones, each zone having a virtual geographical boundary associated with a physical geographical area including at least one facility. It is determined that the vehicle is located within a zone of the zone data record for a preconfigured period of time based on the vehicle location indicator and the zone data record. Responsive to determining that the vehicle is located within the zone for the preconfigured period, performance of the activity at the one or more facilities by the vehicle is determined.

Abstract: A plug deflector includes a body having a first end and a second end opposite the first end, a tool receptacle provided at the first end and defining an internal bore having a first coupling mechanism defined on the internal bore, at least one plug provided at the second end, and a deflector surface provided at an intermediate location between the first and second ends. A system includes a Y-block positioned within a multi-lateral wellbore at a junction of a first wellbore and a second wellbore extending from the first wellbore, the Y-block having a first leg fluidly coupled to the first wellbore and a second leg fluidly coupled to the second wellbore, and a plug deflector coupled to the Y-block.

Abstract: This disclosure may generally relate to drilling operations and, more particularly, to systems and methods for sidetracking an existing well. A bottom hole assembly may comprise a milling assembly, a whipstock coupled to the milling assembly, wherein the whipstock comprises an inclined ramp configured for diverting the milling assembly toward a casing string, and a downhole subassembly coupled to the whipstock, wherein the downhole subassembly comprises a body portion and one or more components on the body portion operable to weaken and/or remove material from the casing string.

Abstract: This disclosure may generally relate to drilling operations and, more particularly, to systems and methods for sidetracking an existing well. A bottom hole assembly may comprise a milling assembly, a whipstock coupled to the milling assembly, wherein the whipstock comprises an inclined ramp configured for diverting the milling assembly toward a casing string, and a downhole subassembly coupled to the whipstock, wherein the downhole subassembly comprises a body portion and one or more components on the body portion operable to weaken and/or remove material from the casing string.

Abstract: A wellbore isolation system is disclosed. The wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore. The deflector includes a channel extending axially through the deflector, and a degradable plug disposed in the channel and engaged with the channel to prevent fluid flow through the channel.

Abstract: A wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore. The deflector includes a channel extending axially through the deflector, and a degradable plug disposed in the channel and engaged with the channel to prevent fluid flow through the channel.

Abstract: A plug deflector includes a body having a first end and a second end opposite the first end, a tool receptacle provided at the first end and defining an internal bore having a first coupling mechanism defined on the internal bore, at least one plug provided at the second end, and a deflector surface provided at an intermediate location between the first and second ends. A system includes a Y-block positioned within a multi-lateral wellbore at a junction of a first wellbore and a second wellbore extending from the first wellbore, the Y-block having a first leg fluidly coupled to the first wellbore and a second leg fluidly coupled to the second wellbore, and a plug deflector coupled to the Y-block.

Abstract: Some embodiments facilitate remote monitoring of an activity at one or more facilities by a vehicle. Data is received at A communications interface from a remote device that is co-located with the vehicle. The data includes a vehicle identifier and a vehicle location indicator, A zone data record is accessed. The zone data record includes a plurality of zones, each zone having a virtual geographical boundary associated with a physical geographical area including at least one facility. It is determined that the vehicle is located within a zone of the zone data record for a preconfigured period of time based on the vehicle location indicator and the zone data record. Responsive to determining that the vehicle is located within the zone for the preconfigured period, performance of the activity at the one or more facilities by the vehicle is determined.

Abstract: Disclosed are expandable bullnose assemblies. One bullnose assembly includes a body and a bullnose tip arranged at a distal end of the body, a compression ring arranged about an exterior of the body and configured to axially translate with respect to the body upon being actuated, and a plurality of collet fingers coupled to and extending between the compression ring and the bullnose tip, each collet finger being pre-compressed such that each collet finger is predisposed to bow radially outwards, wherein, when the compression ring is actuated, the plurality of collet fingers move radially outward from a first diameter to a second diameter that is greater than the first diameter.

Abstract: A wellbore isolation system is disclosed. The wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore. The deflector includes a channel extending axially through the deflector, and a degradable plug disposed in the channel and engaged with the channel to prevent fluid flow through the channel.

Abstract: Disclosed are expandable bullnose assemblies. One bullnose assembly includes a body and a bullnose tip arranged at a distal end of the body, a compression ring arranged about an exterior of the body and configured to axially translate with respect to the body upon being actuated, and a plurality of collet fingers coupled to and extending between the compression ring and the bullnose tip, each collet finger being pre-compressed such that each collet finger is predisposed to bow radially outwards, wherein, when the compression ring is actuated, the plurality of collet fingers move radially outward from a first diameter to a second diameter that is greater than the first diameter.