Abstract: Systems and methods of model or prediction algorithm selection are provided. An autonomous control system may include a perception component that, based on environmental inputs regarding an object(s), a vehicle's operating characteristics, etc., outputs a current state of the vehicle's surrounding environment. This in turn, is used as input to a prediction component comprising a plurality of prediction algorithms. The prediction component outputs a set of predictions regarding the trajectory of the object(s). Accordingly, for each object, a set of trajectories at specific timesteps may be generated by the different prediction algorithms which are input to a planner component. These trajectories may then be analyzed, compared, or otherwise processed to determine which trajectory regarding the object is most accurate. The prediction algorithm or model that produced the most accurate predicted trajectory may then be used for subsequent predictions/timesteps.

Abstract: Compounds useful for biotin-free proximity labeling are provided. Also provided are methods for biotin-free labeling of biomolecules in proximity to a target in a cell, which involve attaching an engineered labeling enzyme to the target; and contacting the cell to a compound as disclosed, which is a substrate of the engineered labeling enzyme and which includes a label moiety, wherein the biomolecules in proximity to the target are labeled.

Abstract: A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a subject and determining changes in fluorescence, the chemigenetic calcium indicator including a ligand binding protein domain having a calcium-binding protein domain and a dye-ligand conjugate attached thereto.

Abstract: Fluorescent compounds are provided, including polycyclic chemical fluorophores, as well as method for making and using such compounds.

Abstract: A flashing assembly and related systems and methods are provided. The flashing assembly comprises a fleece layer, an attachment layer, and a flashing layer located between the fleece layer and the attachment layer. The fleece layer covers a portion of the flashing layer. The flashing assembly is configured to be installed on a building structure.

Abstract: Guide systems for installing aircraft structures are disclosed. An example apparatus includes a first guide structured to be supported by a first hinge component of a first aircraft structure and a second guide structured to be supported by a second hinge component of a second aircraft structure. The first guide is to receive the second guide when the second structure is at an installation angle relative to the first structure. Engagement between the first guide and the second guide to enable rotational movement of the first hinge component and the second hinge component when the second aircraft structure moves to an installed position.

Abstract: The presently-disclosed subject matter includes fluorescent indicators, including bright and targetable red Ca2+ indicators. The presently-disclosed subject matter also includes kits comprising the same as well as methods for using the same to detect a target substance.

Abstract: A dispensing device includes a container, wherein a bottom surface of the container includes a container opening to the interior storage; first and second sliding members that engage with the first and second tracks, respectively; a bowl support connected to the first and second sliding members, and wherein the bowl support is configured to move between a filling position and a serving position; and an actuator including a body including a first end and a second end. When the first end is in a first position, the bowl support is in the filling position. When the first end is in a second position, the bowl support is in the serving position.

Abstract: A fuse holder is disclosed. The fuse holder includes a housing having a fuse compartment and termination compartments, each termination compartment having a cable termination aperture for receiving a cable and a lock pin slot; a bus assembly disposed including current bars having a first end and a second end extending from the termination compartment to the termination compartment, the first end having fuse contacts extending from the first end, the second end including a barb extending from the second end; and, push-in clamps disposed within the termination compartment, the push-in clamps normally biased against the barbs; wherein insertion of an electrical cable into the cable termination aperture depresses and elastically deforms the push-in clamp such that a gap is formed between the barb and the push-in clamp, wherein the push-in clamp continuously applies a biasing force against the electrical cable non-removably clamping the cable into the termination aperture.

Abstract: A flashing assembly and related systems and methods are provided. The flashing assembly comprises a fleece layer, an attachment layer, and a flashing layer located between the fleece layer and the attachment layer. The fleece layer covers a portion of the flashing layer. The flashing assembly is configured to be installed on a building structure.

Abstract: The application discloses a compound having a moiety that is either an affinity tag-containing moiety or a protein-manipulation moiety, a self-labeling protein (SLP) ligand, and a rhodamine dye linking the affinity tag-containing moiety or a protein-manipulation moiety to the SLP ligand. Also disclosed is a complex, which includes the compound and a SLP. Also disclosed is a method that involves contacting the compound and a SLP with a cell, and visualizing fluorescence in the cell or purifying the SLP and associated biological components from the cell.

Abstract: In some embodiments, a system can include a fluid delivery assembly and a drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the drive assembly. When the fluid delivery assembly is releasably coupled to the drive assembly, the drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Abstract: A dispensing device includes a container, wherein a bottom surface of the container includes a container opening to the interior storage; first and second tracks located below the bottom surface of the container on opposing sides of the container opening; first and second sliding members that engage with the first and second tracks, respectively; a bowl support connected to the first and second sliding members, and wherein the bowl support is configured to move between a filling position and a serving position; and a lever including a lever body including a first lever end and a second lever end. When the first lever end is in a first position, the bowl support is in the filling position. When the first lever end is in a second position, the bowl support is in the serving position.

Abstract: Provided are a photoactive fluorophore, a photoactive ligand, and a photoactive complex. The photoactive fluorophore includes a photoactivatable derivative of an azetidine-containing Janelia-Fluor dye. The photoactive ligand includes a photoactive fluorophore and a protein tag. The photoactive complex includes a photoactive ligand conjugated to a protein. Also provided are methods of in vivo labeling with and photoactivation of the photoactive fluorophore, ligand, and complex.

Abstract: A system may include one or both of a light emitter and a light receiver. The system may include an optical filter adjacent one or both of the light emitter or the light receiver. The optical filter includes a wavelength selective scattering layer. The wavelength selective scattering layer may have a near-infrared scattering ratio of less than about 0.9. The filter may have a visible reflective haze ratio of greater than about 0.5. A method may include disposing the wavelength selective scattering layer adjacent one or both of the light emitter and the light receiver. An article may include the optical filter. The wavelength selective scattering layer may have an average near-infrared scattering of less than 60%, an average visible scattering of greater than 10%, and a difference between the % total visible reflectance and the % diffuse visible reflectance of less than 20.

Abstract: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.

Abstract: An antenna element suited for direction finding (DF) with omni-directional radiation patterns utilizing a pair of chevron slots fed using a ridged waveguide magic tee (magic-t) and connected microstrip probes. The provided antenna element provides improved performance, power handling, and improved bandwidth compared to current monocone and/or slot antenna elements. The antenna element may be further realized utilizing additive manufacturing processes in combination with standard metal and polymer production techniques.

Abstract: A fuse holder is disclosed. The fuse holder includes a housing having a fuse compartment and termination compartments, each termination compartment having a cable termination aperture for receiving a cable and a lock pin slot; a bus assembly disposed including current bars having a first end and a second end extending from the termination compartment to the termination compartment, the first end having fuse contacts extending from the first end, the second end including a barb extending from the second end; and, push-in clamps disposed within the termination compartment, the push-in clamps normally biased against the barbs; wherein insertion of an electrical cable into the cable termination aperture depresses and elastically deforms the push-in clamp such that a gap is formed between the barb and the push-in clamp, wherein the push-in clamp continuously applies a biasing force against the electrical cable non-removably clamping the cable into the termination aperture.

Abstract: Systems and methods of model or prediction algorithm selection are provided. An autonomous control system may include a perception component that, based on environmental inputs regarding an object(s), a vehicle's operating characteristics, etc., outputs a current state of the vehicle's surrounding environment. This in turn, is used as input to a prediction component comprising a plurality of prediction algorithms. The prediction component outputs a set of predictions regarding the trajectory of the object(s). Accordingly, for each object, a set of trajectories at specific timesteps may be generated by the different prediction algorithms which are input to a planner component. These trajectories may then be analyzed, compared, or otherwise processed to determine which trajectory regarding the object is most accurate. The prediction algorithm or model that produced the most accurate predicted trajectory may then be used for subsequent predictions/timesteps.

Abstract: A chemigenetic calcium indicator and a method of measuring calcium are provided. The chemigenetic calcium indicator includes a calcium-binding protein domain attached to a ligand binding protein domain. The method of measuring calcium includes administering a chemigenetic calcium indicator to a subject and determining changes in fluorescence, the chemigenetic calcium indicator including a ligand binding protein domain having a calcium-binding protein domain and a dye-ligand conjugate attached thereto.