Abstract: The present disclosure is directed to systems and methods of maintaining databases of biomedical images. A server may aggregate digital pathology records from data sources onto a database. Each record may be generated by a data source using a format, and may identify a biomedical image of a sample and data identifying a subject from which the sample is obtained. The server may receive, from a client device, a query identifying a criterion. The server may access the database to identify a subset of records using the criterion. For each record of the subset, the server may identify a data source that generated the record. The server may select a de-identification policy to apply based on the data source. The server may modify the data in the record according to the de-identification policy and the format. The server may provide, to the client device, the de-identified record.