Patents by Inventor Luke Gilbert

Luke Gilbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR GENE EDITING
    Publication number: 20240309345
    Abstract: Provided herein are, inter alia, fusion proteins, compositions and methods for manipulation of genomes of living organisms.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 19, 2024
    Inventors: Luke Gilbert, James Nunez, Jonathan Weissman, Jin Chen
  • Optimized small guide RNAs and methods of use
    Patent number: 12049624
    Abstract: Methods, compositions, and kits are provided herein for CRISPER/Cas-mediated nucleic acid detection or modification.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: July 30, 2024
    Assignee: The Regents of the University of California
    Inventors: Bo Huang, Baohui Chen, Lei Qi, Luke Gilbert
  • COMPOSITIONS AND METHODS FOR EPIGENOME EDITING
    Publication number: 20230212323
    Abstract: Provided herein are, inter alia, compositions and methods for modulating gene expression.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 6, 2023
    Inventors: Luke Gilbert, Jonathan Weissman, James Nunez, Greg Pommier
  • Compositions and Methods for Gene Editing
    Publication number: 20230124253
    Abstract: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
    Type: Application
    Filed: July 29, 2022
    Publication date: April 20, 2023
    Inventors: Jin Chen, Luke Gilbert, James Nunez, Jonathan Weissman
  • COMPOSITIONS AND METHODS FOR GENE EDITING
    Publication number: 20230103909
    Abstract: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
    Type: Application
    Filed: April 21, 2022
    Publication date: April 6, 2023
    Inventors: Jin Chen, Luke Gilbert, James Nunez, Jonathan Weissman
  • Compositions and methods for gene editing
    Patent number: 11434491
    Abstract: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: September 6, 2022
    Assignee: The Regents of the University of California
    Inventors: Jin Chen, Luke Gilbert, James Nunez, Jonathan Weissman
  • Screening for Inhibitors of Prostaglandin E Synthase 3 Useful for Treatment of Prostate Cancer
    Publication number: 20220091102
    Abstract: Methods and compositions are provided for screening candidate agents for inhibition of prostaglandin E synthase 3 (PTGES3) and anti-cancer activity against prostate cancer. In one aspect, a method of screening for a prostaglandin E synthase 3 (PTGES3) inhibitor for treating prostate cancer is provided, the method comprising: a) contacting PTGES3 with a candidate agent; and b) measuring inhibition of PTGES3 activity by the candidate agent. Screening assays may include determining the effectiveness of candidate PTGES3 inhibitors in reducing proliferation, survival, or androgen receptor abundance of prostate cancer cells.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Inventors: Luke Gilbert, Felix Feng, Haolong Li
  • COMPOSITIONS AND METHODS FOR GENE EDITING
    Publication number: 20210139918
    Abstract: Provided herein are, inter alia, compositions and methods for manipulation of genomes of living organisms.
    Type: Application
    Filed: October 19, 2020
    Publication date: May 13, 2021
    Inventors: Jin Chen, Luke Gilbert, James Nunez, Jonathan Weissman
  • OPTIMIZED SMALL GUIDE RNAS AND METHODS OF USE
    Publication number: 20210123046
    Abstract: Methods, compositions, and kits are provided herein for CRISPER/Cas-mediated nucleic acid detection or modification.
    Type: Application
    Filed: September 25, 2020
    Publication date: April 29, 2021
    Inventors: Bo Huang, Baohui Chen, Lei Qi, Luke Gilbert
  • Optimized small guide RNAs and methods of use
    Patent number: 10822606
    Abstract: Methods, compositions, and kits are provided herein for CRISPER/Cas-mediated nucleic acid detection or modification.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: November 3, 2020
    Assignee: The Regents of the University of California
    Inventors: Bo Huang, Baohui Chen, Lei Qi, Luke Gilbert
  • COMPOSITIONS AND METHODS FOR CRISPR-BASED SCREENING
    Publication number: 20190300868
    Abstract: Provided herein are compositions and methods for CRISPR-based screening.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 3, 2019
    Inventors: Luke Gilbert, Maximilian A. Horlbeck, Marco Jost, Jonathan Weissman