Patents by Inventor Luke Guo

Luke Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermal blood clot formation and use in microfluidic device valving applications
    Patent number: 8845979
    Abstract: The present invention provides a method of forming a blood-clot microvalve by heating blood in a capillary tube of a microfluidic device. Also described are methods of modulating liquid flow in a capillary tube by forming and removing a blood-clot microvalve.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: September 30, 2014
    Assignee: California Institute of Technology
    Inventors: Yu-Chong Tai, Wendian Shi, Luke Guo
  • USING BLOOD CLOT IN MICROFLUIDIC VALVING APPLICATIONS
    Publication number: 20120064552
    Abstract: The present invention provides a method of forming a blood-clot microvalve by heating blood in a capillary tube of a microfluidic device. Also described are methods of modulating liquid flow in a capillary tube by forming and removing a blood-clot microvalve.
    Type: Application
    Filed: September 14, 2011
    Publication date: March 15, 2012
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Yu-Chong Tai, Wendian Shi, Luke Guo
  • Immunoliposome composition for targeting to a HER2 cell receptor
    Publication number: 20060269542
    Abstract: An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapped drug.
    Type: Application
    Filed: April 20, 2006
    Publication date: November 30, 2006
    Inventors: Kristen Hjortsvang, Luke Guo, Frances Wong, Azar Najafi, Anthony Huang, Robert Abra, Laura Kelley
  • Method of pulmonary administration of an agent
    Publication number: 20050025822
    Abstract: A method for administering a therapeutic or diagnostic agent to a subject is described. The method includes providing a suspension of liposomes comprised of one or more of vesicle-forming lipids selected from (i) a vesicle-forming lipid derivatized with a hydrophilic polymer and (ii) a neutral lipopolymer, said liposomes being associated with said therapeutic or diagnostic agent, forming an aerosol of said liposome suspension; and administering the aerosol to the subject by inhalation. The liposome formulation delivers intact liposomal particles to the respiratory tract of said subject to form a depot of therapeutic agent therein with no observable provocation of an immune response, as measured by neutrophil or macrophage cell count in the lung after administration.
    Type: Application
    Filed: May 27, 2004
    Publication date: February 3, 2005
    Inventors: Frances Wong, Anuk Das, Jonathan Seideman, Luke Guo, Anthony Huang