Patents by Inventor Luke Judge

Luke Judge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determining cellular protein homeostasis
    Patent number: 11020463
    Abstract: The present invention provides assays and compositions to identify the risk of toxicity in a patient population with genotypic variations in specific proteins and/or protein complexes within the patient population.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: June 1, 2021
    Assignees: The J. David Gladstone Institutes, The Regents of the University of California
    Inventors: Bruce R. Conklin, Luke Judge
  • METHOD OF DETERMINING CELLULAR PROTEIN HOMEOSTASIS
    Publication number: 20190015486
    Abstract: The present invention provides assays and compositions to identify the risk of toxicity in a patient population with genotypic variations in specific proteins and/or protein complexes within the patient population.
    Type: Application
    Filed: August 8, 2016
    Publication date: January 17, 2019
    Inventors: Bruce R. Conklin, Luke Judge
  • Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
    Publication number: 20050119332
    Abstract: The present invention provides novel compounds of formula 1a, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTP?, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.
    Type: Application
    Filed: November 8, 2004
    Publication date: June 2, 2005
    Inventors: Lone Jeppesen, Henrik Andersen, Ole Olsen, Luke Judge, Daniel Holsworth, Farid Bakir, Frank Axe, Yu Ge