Abstract: A compression garment for implementing circulatory-related disorder therapy includes a plurality of chambers. In some implementations, the compression garment further includes air supply tubes and tube guides for maintaining the air supply tubes on a predetermined pathway in or on the garment. In some implementations, the compression garment further includes three or more layers forming the macro-chambers and air supply channels for supplying air to the macro-chamber. In some implementations, the compression garment further includes a flexible foot chamber support assembly that allows bending around a periphery of a user's foot. In some implementations, the compression garment further includes chamber valves and a main air supply valve pneumatically connected to a central air supply line and configured to control the supply of pressurized air to at least two of the chamber valves.