Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides column 50 a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.

Abstract: A system and method for separating the functions of a liquid chromatography (LC) system into physically separate systems that allow for a more versatile LC system, wherein an LC device provides column 50 a liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port, and providing an attachable module containing a module input port, a column, a heater for the column, and at least one detector for on-column detection, then attaching the module to the LC device using a press-fit connection that enables the sample in the solvent to be pumped through the column to the at least one detector in order to separate, identify and quantify substances in the sample and transmit results from the at least one detector to the LC system for collection and analysis.

Abstract: A system and method for performing UV LED-based absorption detection for capillary liquid chromatography for detecting and quantifying compounds in a liquid, wherein a simplified system eliminates the need for a beam splitter and a reference cell by using a stable UV source, and power requirements are reduced, resulting in a portable and substantially smaller system with relatively low detection limits.

Abstract: A system and method for performing liquid chromatography for separating molecules in a liquid solution, wherein a single column includes two of more separation segments, each separation segment having a separate detector immediately after each separation segment, wherein a mobile phase is inserted into a first separation segment and moves through the column until passing through a last separation segment, and then using the data from the detectors to perform compound identification.

Abstract: A flow meter enables a time-of-flight method for non-invasively measuring liquid flow in a fluid conduit. The flow meter comprises a perturbing element in the form of a phase changing device, a heat transfer device, an electrochemical perturbing device or a photochemical perturbing device, and a conductivity detection device spaced downstream from the perturbing element. The perturbing element is applied to a small section of the conduit to cause a perturbation in a portion of the liquid flowing therethrough. This perturbation causes a change in conductivity a liquid plug, and the affected liquid plug continuous to flow in the fluid conduit toward the conductivity detection device. The conductivity detection device then senses the change in conductivity resulting from the perturbation, and flow rate or velocity is determined from the time of detection and the distance between the point of perturbation and the point of conductivity change detection.

Abstract: A contactless, resistive heating device applies heat energy non-invasively to a target zone of liquid contained by a non-conductive substrate or capillary. The heating device supplies an AC signal to two spaced-apart electrodes, which are disposed externally of the substrate. A circuit is established in which the source of the AC signal is capacitively coupled with the liquid through each electrode. The zone of liquid between the electrodes is heated due to the resulting flow of electrical current across the zone.

Abstract: A photothermal absorbance detection apparatus for performing absorbance measurements of analytes in capillaries having non-conductive walls comprises a light source and a conductivity detection device. The conductivity detection device includes an applied voltage source and at least two electrodes disposed adjacent to the walls of a section of capillary. By using the light source to heat the analytes, the resulting change in conductivity of the liquid containing the analytes can be detected in the liquid. A measurement of absorbance can then be obtained as a function of the change in conductivity.