Abstract: A device implementing a system for anonymizing user data provided for server-side operations includes a processor configured to receive user input including a search term, wherein first and second data structures are stored on the device, the first data structure including user interest data items that correspond to prior user activity, the second data structure including topic data items mapped to the user interest data items, the topic data items being broader than the user interest data items. The processor accesses the second data structure to obtain one or more topic data items. The processor transmits, to a server, the search term and one or more topic data items for obtaining a query suggestion or search result. The processor receives, from the server, the query suggestion or search result, the query suggestion or search result having been obtained based on the search term and one or more topic data items.

Abstract: The invention relates to the improvement of endonuclease-based antimicrobials by blocking DNA repair of double-strand break(s) (DSB(s)) in prokaryotic cells. In this respect, the invention especially concerns a method involving blocking DNA repair after a nucleic acid has been submitted to DSB, in particular by a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated programmable double-strand endonuclease. The invention particularly relates to the use of an exogenous molecule that inhibits DNA repair, preferably a protein that binds to the ends of the double-stranded break to block DSB repair. The invention also relates to vectors, particularly phagemids and plasmids, comprising nucleic acids encoding nucleases and Gam proteins, and a pharmaceutical composition and a product containing these vectors and their application.

Abstract: Systems and processes for providing personalized suggestions indicating that a task may be performed using a digital assistant of an electronic device are provided. An example method includes, at an electronic device with a display, receiving context data associated with the electronic device; determining, based on the context data, a task that may be performed by a digital assistant of the electronic device in response to a natural-language expression; determining, based on the context data, whether suggestion criteria associated with the determined task are satisfied; and in accordance with a determination that the suggestion criteria are satisfied, providing a suggestion indicating that the determined task may be performed using the digital assistant of the electronic device.

Abstract: Systems and processes for providing personalized suggestions indicating that a task may be performed using a digital assistant of an electronic device are provided. An example method includes, at an electronic device with a display, receiving context data associated with the electronic device; determining, based on the context data, a task that may be performed by a digital assistant of the electronic device in response to a natural-language expression; determining, based on the context data, whether suggestion criteria associated with the determined task are satisfied; and in accordance with a determination that the suggestion criteria are satisfied, providing a suggestion indicating that the determined task may be performed using the digital assistant of the electronic device.

Abstract: The invention relates to the improvement of endonuclease-based antimicrobials by blocking DNA repair of double-strand break(s) (DSB(s)) in prokaryotic cells. In this respect, the invention especially concerns a method involving blocking DNA repair after a nucleic acid has been submitted to DSB, in particular by a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated programmable double-strand endonuclease. The invention particularly relates to the use of an exogenous molecule that inhibits DNA repair, preferably a protein that binds to the ends of the double-stranded break to block DSB repair. The invention also relates to vectors, particularly phagemids and plasmids, comprising nucleic acids encoding nucleases and Gam proteins, and a pharmaceutical composition and a product containing these vectors and their application.

Abstract: A method and apparatus of a device that re-rank a plurality of search results received from a search server on the device is described. In an exemplary embodiment, the device receives, with a browser of the device, a search query from a user. The device further sends the search query to a search server. In addition, the device receives the plurality of search results from the search server, wherein the plurality of search results is ranked according to a first ranking. The device also retrieves browser history of the user, wherein the browser history is collected on the device without revealing the browser history to the search server. The device further re-ranks the plurality of search results according to a second ranking based on at least the browser history. In addition, the device presents the plurality of search results using the second ranking.

Abstract: A method and apparatus of a device that generates a re-ranking model used to re-rank a plurality of search results on a client device is described. In an exemplary embodiment, the device receives a crowd-sourced intra-domain model from a server, where the intra-domain model is a search result re-ranking model generated based on at least device interactions of a plurality of users interacting with a plurality of other devices. The device further generates a re-ranking model from the crowd-sourced intra-domain model and a local model, where the local model includes private data representing a device user's interaction with that device and the re-ranking model is used to re-rank a plurality of search results.

Abstract: A method and apparatus of a device that performs a multi-domain query search is described. In an exemplary embodiment, the device receives a query prefix from a client of a user. The device further determines a plurality of search completions across the plurality of separate search domains. In addition, the device ranks the plurality of search completions based on a score calculated for each of the plurality of search completions determined by a corresponding search domain, where at least one of the plurality of search completions is used to generate a plurality of search results without an indication from the user and in response to receiving the query prefix.

Abstract: A method and apparatus of a device that re-rank a plurality of search results is described. In an exemplary embodiment, the device receives a search query from a user and generates the plurality of search results over a plurality of search domains, wherein the plurality of search results is ranked according to a first ranking. The device additionally generates a re-ranking model, where the re-ranking model includes a plurality of intra-domain models that are generated based on at least based on-device interactions of a plurality of users interacting with a plurality of other devices and each of the plurality of search domains corresponds to one of the plurality of intra-domain models. The device further re-ranks the plurality of search results using the re-ranking model and presents the plurality of search results using the second ranking.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: Systems and processes for providing personalized suggestions indicating that a task may be performed using a digital assistant of an electronic device are provided. An example method includes, at an electronic device with a display, receiving context data associated with the electronic device; determining, based on the context data, a task that may be performed by a digital assistant of the electronic device in response to a natural-language expression; determining, based on the context data, whether suggestion criteria associated with the determined task are satisfied; and in accordance with a determination that the suggestion criteria are satisfied, providing a suggestion indicating that the determined task may be performed using the digital assistant of the electronic device.

Abstract: A device implementing a system for providing query completion suggestions includes at least one processor configured to receive a partial query, and derive one or more query completion suggestions for the partial query from content items that are locally stored on the device, each respective query completion suggestion being associated with metadata extracted from one of the content items from which the respective query completion suggestion was derived. The at least one processor is further configured to rank the one or more query completion suggestions based at least in part on the metadata associated with each of the one or more query completion suggestions. The at least one processor is further configured to provide, for display, at least one of the one or more ranked query completion suggestions.

Abstract: A device implementing a system for anonymizing user data provided for server-side operations includes a processor configured to receive user input including a search term, wherein first and second data structures are stored on the device, the first data structure including user interest data items that correspond to prior user activity, the second data structure including topic data items mapped to the user interest data items, the topic data items being broader than the user interest data items. The processor accesses the second data structure to obtain one or more topic data items. The processor transmits, to a server, the search term and one or more topic data items for obtaining a query suggestion or search result. The processor receives, from the server, the query suggestion or search result, the query suggestion or search result having been obtained based on the search term and one or more topic data items.

Abstract: A device implementing a system for anonymizing user data provided for server-side operations includes a processor configured to receive user input including a search term, wherein first and second data structures are stored on the device, the first data structure including user interest data items that correspond to prior user activity, the second data structure including topic data items mapped to the user interest data items, the topic data items being broader than the user interest data items. The processor accesses the second data structure to obtain one or more topic data items. The processor transmits, to a server, the search term and one or more topic data items for obtaining a query suggestion or search result. The processor receives, from the server, the query suggestion or search result, the query suggestion or search result having been obtained based on the search term and one or more topic data items.

Abstract: The invention relates to the improvement of endonuclease-based antimicrobials by blocking DNA repair of double-strand break(s) (DSB(s)) in prokaryotic cells. In this respect, the invention especially concerns a method involving blocking DNA repair after a nucleic acid has been submitted to DSB, in particular by a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated programmable double-strand endonuclease. The invention particularly relates to the use of an exogenous molecule that inhibits DNA repair, preferably a protein that binds to the ends of the double-stranded break to block DSB repair. The invention also relates to vectors, particularly phagemids and plasmids, comprising nucleic acids encoding nucleases and Gam proteins, and a pharmaceutical composition and a product containing these vectors and their application.

Abstract: A device implementing a system for determining an answer to a question includes a processor configured to receive a question from a client device, and send the question to a first information domain comprising plural search subdomains, each of the plural search subdomains being configured to provide a respective candidate answer to the question in a format that differs from those provided by the other search subdomains of the plural search subdomains. The processor is further configured to receive, in response to sending the question, the candidate answer from each of the plural search subdomains, and provide at least one of the candidate answers to the client device, for providing an answer to the question based on the at least one of the candidate answers.

Abstract: A method and apparatus of a device that selects an application state for use in a multi-device search is described. In this embodiment, the device detects, on the device, that the application state has been selected as a query result for a device-level search on that device. The device further transmits the application state to a server, wherein the application state is to be indexed with other application states from other devices.

Abstract: A device implementing a system for anonymizing user data provided for server-side operations includes a processor configured to receive user input including a search term, wherein first and second data structures are stored on the device, the first data structure including user interest data items that correspond to prior user activity, the second data structure including topic data items mapped to the user interest data items, the topic data items being broader than the user interest data items. The processor accesses the second data structure to obtain one or more topic data items. The processor transmits, to a server, the search term and one or more topic data items for obtaining a query suggestion or search result. The processor receives, from the server, the query suggestion or search result, the query suggestion or search result having been obtained based on the search term and one or more topic data items.

Abstract: A device implementing a system for providing query completion suggestions includes at least one processor configured to receive a partial query, and derive one or more query completion suggestions for the partial query from content items that are locally stored on the device, each respective query completion suggestion being associated with metadata extracted from one of the content items from which the respective query completion suggestion was derived. The at least one processor is further configured to rank the one or more query completion suggestions based at least in part on the metadata associated with each of the one or more query completion suggestions. The at least one processor is further configured to provide, for display, at least one of the one or more ranked query completion suggestions.