Patents by Inventor Lun-Kelvin Tsou

Lun-Kelvin Tsou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Poly heterocyclic conjugates and their pharmaceutical uses
    Patent number: 11878986
    Abstract: Compounds of Formula (I) shown below and a pharmaceutical composition containing one of the compounds: Each of the variables is defined herein. Also disclosed is a method of treating a condition associated with uncontrolled cell growth with a compound of Formula (I).
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: January 23, 2024
    Assignee: National Health Research Institutes
    Inventors: Lun Kelvin Tsou, Kuan-Hsun Huang, Chiung-Tong Chen, Chuan Shih
  • PTGR2 inhibitors and their use
    Patent number: 11851435
    Abstract: Disclosed are compounds of formula (I) as follows: in which each of R1, R2, R3, R4, R5, L1, W, and Het is defined herein. Also provides are a method of inhibiting prostaglandin reductase 2 (“PTGR2”) using such a compound and a pharmaceutical composition containing same.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: December 26, 2023
    Assignees: National Health Research Institutes, National Taiwan University
    Inventors: Lun Kelvin Tsou, Ming-Shiu Hung, Chieh Wen Chen, Meng-Lun Hsieh, Yi-Cheng Chang, Lee Ming Chuang
  • PTGR2 INHIBITORS AND THEIR USE
    Publication number: 20230279008
    Abstract: Disclosed are compounds of formula (I) as follows: in which each of R1, R2, R3, R4, R5, L1, W, and Het is defined herein. Also provides are a method of inhibiting prostaglandin reductase 2 (“PTGR2”) using such a compound and a pharmaceutical composition containing same.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 7, 2023
    Inventors: Lun Kelvin Tsou, Ming-Shiu Hung, Chieh Wen Chen, Meng-Lun Hsieh, Yi-Cheng Chang, Lee Ming Chuang
  • POLY HETEROCYCLIC CONJUGATES AND THEIR PHARMACEUTICAL USES
    Publication number: 20210403483
    Abstract: Compounds of Formula (I) shown below and a pharmaceutical composition containing one of the compounds: Each of the variables is defined herein. Also disclosed is a method of treating a condition associated with uncontrolled cell growth with a compound of Formula (I).
    Type: Application
    Filed: June 16, 2021
    Publication date: December 30, 2021
    Inventors: Lun Kelvin Tsou, Kuan-Hsun Huang, Chiung-Tong Chen, Chuan Shih
  • Heterocyclic compounds and use thereof
    Patent number: 9926298
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: March 27, 2018
    Assignee: National Health Research Institutes
    Inventors: Kak-Shan Shia, Jiing-Jyh Jan, Lun Kelvin Tsou, Chiung-Tong Chen, Yu-Sheng Chao
  • HETEROCYCLIC COMPOUNDS AND USE THEREOF
    Publication number: 20180009786
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 11, 2018
    Inventors: Kak-Shan Shia, Jiing-Jyh Jan, Lun Kelvin Tsou, Chiung-Tong Chen, Yu-Sheng Chao
  • Heterocyclic compounds and use thereof
    Patent number: 9862703
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: January 9, 2018
    Assignee: National Health Research Institutes
    Inventors: Kak-Shan Shia, Jiing-Jyh Jan, Lun Kelvin Tsou, Chiung-Tong Chen, Yu-Sheng Chao
  • Dipicolylamine derivatives and their pharmaceutical uses
    Patent number: 9388193
    Abstract: Dipicolylamine compounds of Formula (I) set forth herein. Also disclosed are pharmaceutical compositions containing metal ions and these compounds. Further disclosed is a method for treating a condition associated with cells containing inside-out phosphatidylserine, with these compounds.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: July 12, 2016
    Assignees: National Health Research Institutes, Molecular Targeting Technologies, Inc.
    Inventors: Chiung-Tong Chen, Kak-Shan Shia, Chien-Huang Wu, Lun-Kelvin Tsou, Yu-Sheng Chao
  • HETEROCYCLIC COMPOUNDS AND USE THEREOF
    Publication number: 20160083369
    Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.
    Type: Application
    Filed: September 21, 2015
    Publication date: March 24, 2016
    Inventors: Kak-Shan Shia, Jiing-Jyh Jan, Lun Kelvin Tsou, Chiung-Tong Chen, Yu-Sheng Chao
  • DIPICOLYLAMINE DERIVATIVES AND THEIR PHARMACEUTICAL USES
    Publication number: 20150336976
    Abstract: Dipicolylamine compounds of Formula (I) set forth herein. Also disclosed are pharmaceutical compositions containing metal ions and these compounds. Further disclosed is a method for treating a condition associated with cells containing inside-out phosphatidylserine, with these compounds.
    Type: Application
    Filed: May 14, 2015
    Publication date: November 26, 2015
    Inventors: Chiung-Tong Cheng, Kak-Shan Shia, Chien-Huang Wu, Lun-Kelvin Tsou, Yu-Sheng Chao