Abstract: A real time and quantitative method of measuring traction force of living cells include the following procedures. Place AT-cut and BT-cut quartz crystals of the same frequency, surface morphology and/or modified with the same cell adhesion molecules in petri dishes or detection cells; add the cells to the petri dishes or detection cells, the cell traction force at arbitrary time t during adhesion of the cells or under different internal/external environmental stimulations is estimated by the following equation: ?St=(KAT?KBT)?1[tqAT?ftAT/frAT?tqBT?ftBT/frBT]. The method can be used to track the dynamic changes of cells generated force during the adhesion of cells and under different internal/external environmental stimulations, such as the effects of drugs. The drugs can be added before or after the adhesion of the cells. This method is suitable for all adherent cells, including primary cells and passage cells.

Abstract: Provided are a class of vancomycin derivatives with a structure as shown in the general formula below and pharmaceutically acceptable salts thereof, a preparation method, a pharmaceutical composition containing the compound thereof, and the use of these compounds in preparing drugs for treating and/or preventing bacterial infection diseases, in particular drugs for treating infection diseases caused by Gram-positive bacteria.

Abstract: A real time and quantitative method of measuring traction force of living cells include the following procedures. Place AT-cut and BT-cut quartz crystals of the same frequency, surface morphology and/or modified with the same cell adhesion molecules in petri dishes or detection cells; add the cells to the petri dishes or detection cells, the cell traction force at arbitrary time t during adhesion of the cells or under different internal/external environmental stimulations is estimated by the following equation: ?St=(KAT?KBT)?1[tqAT?ftAT/frAT?tqBT?ftBT/frBT]. The method can be used to track the dynamic changes of cells generated force during the adhesion of cells and under different internal/external environmental stimulations, such as the effects of drugs. The drugs can be added before or after the adhesion of the cells. This method is suitable for all adherent cells, including primary cells and passage cells.

Abstract: Provided are a class of vancomycin derivatives with a structure as shown in the general formula below and pharmaceutically acceptable salts thereof, a preparation method, a pharmaceutical composition containing the compound thereof, and the use of these compounds in preparing drugs for treating and/or preventing bacterial infection diseases, in particular drugs for treating infection diseases caused by Gram-positive bacteria.

Abstract: The present invention provides a method, communication system, and Internet Call Waiting/Holding (ICW/H) server for providing internet call waiting service without dropping the connection between a computer and an Internet Service Provider (ISP). A computer, via a modem or the like, initiates an internet call waiting connection between the computer and the ISP via a switch. The ISP assigns a dynamic Internet Protocol (IP) address to the computer for the internet call waiting connection. The computer sends the directory number and the dynamic IP address of the computer to an Internet Call Waiting/Holding (ICW/H) server, which stores them. The ICW/H server sends a message to the switch indicating that the call waiting service is active. The switch, upon receiving an incoming call request intended for the computer while the internet call waiting connection is active, routes the incoming call request to the ICW/H server.