Abstract: An in-situ cultivation system of a deep-sea hydrothermal metallic sulfide deposits includes a hydrothermal metallic sulfide deposit mound body, a well casing, a well head control flow guide device, a fluid mixing control hood; the hydrothermal metallic sulfide deposit mound body includes a confining bed, a hydrothermal fluid enriching bed and mound body bedrock; perforations are formed at casing wall of the well casing; the well head flow control device is provided at top of the well casing; a lower opening is formed at bottom of the fluid mixing control hood and is sleeved on four sides of the top of the well casing; an upper opening is formed at top of the fluid mixing control hood; a plurality of fluid holes are formed at a lateral wall of the fluid mixing control hood; and a sulfide coating is applied to inner wall of the fluid mixing control hood.