Abstract: A coupling assembly for coupling a rod to a bone anchoring element is provided, wherein the coupling assembly includes a receiving part having a first end, a second end, a central axis extending through the first end and second end, an accommodation space for accommodating a head of an anchoring element, a bore extending from the accommodation space to the first end, and a recess for receiving a rod. The accommodation space has an opening at the second end sized to permit insertion of a head of the bone anchoring element. The coupling assembly further includes a retainer element configured to be positioned at least partially in the accommodation space and being radially expandable and/or compressible to allow retaining a head inserted through the opening. The retainer element is held in position adjacent the opening by an engagement structure provided at or in the accommodation space.

Abstract: A polyaxial bone anchoring device includes a bone anchoring element having a head, a receiving part having a channel for receiving a rod and an accommodation space for pivotably holding the head, and a pressure member having a pressure exerting surface and a deformable portion with a free end. The deformable portion is adjustable from a first configuration where a first part of the deformable portion is supported at a first axial position relative to the receiving part while a second part of the deformable portion protrudes further radially into the channel than parts of the deformable portion positioned axially above the second part, to a second configuration where the second part of the deformable portion is deformed radially outwardly and the pressure exerting surface is shifted lower axially to exert pressure on the head while the first part of the deformable portion remains supported at the first axial position.

Abstract: A polyaxial bone anchoring device is provided comprising a bone anchoring element having a shank to be anchored in a bone and a head; a receiving part coupled to the shank and configured to pivotably receive the head, and having a channel for receiving a rod and a longitudinal axis; a pressure member configured to be positioned in the receiving part; a locking member insertable into the channel; wherein the pressure member has a deformable portion; and wherein, when the locking member is advanced into the channel in the direction of the longitudinal axis, the locking member in moveable from a position where it contacts the pressure member resulting in a load applied to the pressure member that clamps the head, to a position where the locking member contacts the pressure member such that the deformable portion is deformed and the locking member contacts the rod and clamps the rod.

Abstract: A coupling assembly for coupling a rod to a bone anchoring element, including a receiving part having first and second ends, a recess at the first end for the rod, and an accommodation space for a head of the bone anchoring element, the accommodation space having an opening at the second end to permit insertion of the head into the receiving part, a retainer element configured to be arranged at least partially in the accommodation space and to hold at least part of the head, and a spring element configured to be arranged at least partially in the accommodation space and to be compressed in an axial direction. The retainer element and the spring element are separate parts. When the retainer element and the spring element are in the accommodation space of the receiving part in a first position, the spring element extends into the recess of the receiving part.

Abstract: A method performed at a mobile transport unit is disclosed. In the method, parameters are determined by using sensors of the transport unit. The parameters include characteristics of the transport unit and/or characteristics of a consignment transported by the transport unit. In the method, the parameters are transmitted to a routing system, which determines a transport route for the transport unit, a need that waypoints/timing of an existing transport route of the transport unit has to be changed to obtain a changed transport route, or a need for a specific handling of the consignment. In the method, an instruction is received that is a routing instruction from the routing system pertaining to the determined transport route for the transport unit, to a transfer of the consignment from the transport unit to another transport unit, or to how the consignment shall be handled by the transport unit.

Abstract: A method for routing is disclosed. The method involves obtaining information on a plurality of to-be-transported entities (TBTEs) that are each associated with a respective pick-up position and a respective drop-off position; determining a set of one or more transport routes (TRs), each of the TRs associated with a respective transport entity (TE) and defining a respective sequence of waypoints, wherein the set of TRs is determined to at least fulfil a criterion that, for each of the TBTEs, the pick-up position and drop-off position are associated with respective waypoints of the same respective TR or the pick-up position is associated with a respective waypoint of one TR and the drop-off position is associated with a respective waypoint of another TR that is connected with the one TR; and providing respective representations of at least a part of the TRs to the respective TEs associated with the TRs.

Abstract: A membrane reactor for the manufacture of plant protein hydrolysates, the membrane reactor comprising a substrate vessel adapted to provide a plant protein substrate to an enzyme source, a continuously stirred reactor comprising the enzyme source, and an ultrafiltration module comprising a membrane with a molecular cut-off wherein the membrane is adapted to allow passage of the plant protein hydrolysate while retaining the enzyme.

Abstract: The present invention provides a polynucleotide or a pair of polynucleotides encoding an enzyme having nitrile hydratase (NHase) [E.C. 4.2.1.84] activity. Furthermore, a vector and a host comprising the disclosed polynucleotide or pair of polynucleotides and methods for the production of the same are provided. Moreover, the invention relates to a pair of polypeptides or a fusion protein having NHase activity, an antibody specifically binding to the pair of polypeptides or fusion protein, a primer or probe, which specifically hybridizes under stringent conditions to the disclosed polynucleotide or either one of the pair of polynucleotides, a composition comprising the polynucleotide or pair of polynucleotides, the pair of polypeptides or fusion protein, the antibody and/or one or more primers or probes of the invention and a method for the production of amides comprising the enantioselective conversion of nitriles.

Abstract: The present invention provides a polynucleotide or a pair of polynucleotides encoding an enzyme having nitrile hydratase (NHase) [E.C. 4.2.1.84] activity. Furthermore, a vector and a host comprising the disclosed polynucleotide or pair of polynucleotides and methods for the production of the same are provided. Moreover, the invention relates to a pair of polypeptides or a fusion protein having NHase activity, an antibody specifically binding to the pair of polypeptides or fusion protein, a primer or probe, which specifically hybridizes under stringent conditions to the disclosed polynucleotide or either one of the pair of polynucleotides, a composition comprising the polynucleotide or pair of polynucleotides, the pair of polypeptides or fusion protein, the antibody and/or one or more primers or probes of the invention and a method for the production of amides comprising the enantioselective conversion of nitrites.

Abstract: The invention relates to an armature for an electromagnetic actuator, having a guide pin that is connected to an armature plate, characterized in that the armature plate (3) is formed by a frame element (4) that comprises soft-magnetic iron and is connected to the guide pin (2), and at least one plate element (5) that comprises a soft-magnetic material and is held in the frame element (4).

Abstract: The invention relates to an armature for an electromagnetic actuator, having a guide pin that is connected to an armature plate, characterized in that the armature plate (3) is formed by a frame element (4) that comprises soft-magnetic iron and is connected to the guide pin (2), and at least one plate element (5) that comprises a soft-magnetic material and is held in the frame element (4).

Abstract: An electromagnetic actuator for operating a cylinder valve in an internal combustion engine includes first and second housings secured to one another. Each housing has a cavity and a through bore extending therefrom. First and second electromagnets are disposed in the cavity of the respective housings. Each electromagnet has a yoke, a coil and a pole face. The pole faces are oriented toward and spaced from one another, and a reciprocating armature is disposed between the pole faces. A spring which urges the armature away from the first electromagnet has an end oriented away from the armature. A support cap is axially insertable in the through bore of the first electromagnet and includes a cap base having an inner face supporting the spring end. A locking arrangement secures the support cap to the housing and has a component axially insertable in the through bore with the support cap.

Abstract: An electromagnetic actuator for operating a cylinder valve in an internal combustion engine includes first and second housings secured to one another. Each housing has a cavity and a through bore extending therefrom. First and second electromagnets are disposed in the cavity of the respective housings. Each electromagnet has a yoke, a coil and a pole face. The pole faces are oriented toward and spaced from one another, and a reciprocating armature is disposed between the pole faces. A spring which urges the armature away from the first electromagnet has an end oriented away from the armature. A support cap is axially insertable in the through bore of the first electromagnet and includes a cap base having an inner face supporting the spring end. A locking arrangement secures the support cap to the housing and has a component axially insertable in the through bore with the support cap.

Abstract: A method for separating enantiomers of a derivative of an aryloxipropanolamine is disclosed, characterized in that the derivative is contacted with a chiral solid-phase chromatography material containing molecular imprints of an optically pure enantiomer of the derivative to be separated.