Patents by Inventor Luuk Elard DE VRIES

Luuk Elard DE VRIES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF
    Publication number: 20220127232
    Abstract: Compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.
    Type: Application
    Filed: February 7, 2020
    Publication date: April 28, 2022
    Inventors: Ottavio ARANCIO, Elisa ZUCCARELLO, Elisa CALCAGNO, Donald W. LANDRY, Shixian DENG, Jole FIORITO, Luuk Elard DE VRIES, Christopher John YARNOLD, Richard Scott JONES, Julian Hugh ROWLEY
  • HISTONE ACETYLTRANSFERASE (HAT) REGULATORS AND USES THEREOF
    Publication number: 20220125748
    Abstract: The invention provides for compounds that are HAT activators or inhibitors. The invention further provides a method for treating neurodegenerative diseases, cancer and other malignant conditions, or to increase memory in a subject not suffering from a neurodegenerative disease by administering HAT activators or inhibitors to a subject in need thereof. The method further comprises co-administration of HD AC inhibitors with HAT activators or HD AC activators with HAT inhibitors.
    Type: Application
    Filed: February 7, 2020
    Publication date: April 28, 2022
    Inventors: Ottavio ARANCIO, Donald W. LANDRY, Shixian DENG, Jennifer Effie AMENGUAL, Elisa ZUCCARELLO, Jole FIORITO, Yuxuan LIU, Elisa CALCAGNO, Luuk Elard DE VRIES