Abstract: Methods and materials for treating a mammal having Alzheimer's disease (AD) are described. For example, one or more Zika virus (ZIKV) polypeptides can be administered to a mammal having, or at risk of developing, AD to treat the mammal.

Abstract: This document provides methods and materials for treating a mammal having Alzheimer's disease (AD). For example, one or more Zika virus (ZIKV) polypeptides can be administered to a mammal having, or at risk of developing, AD to treat the mammal.

Abstract: The present invention publicly discloses a self-locking mechanism of a manually tightened drill chuck, including a ratchet wheel, a clamp bearing, at least one resilient pawl, and a clip ring, wherein said ratchet wheel is fixed in connection with the main unit of said manually tightened drill chuck, and on its back there are provided ratchet teeth facing the end surface of said main unit; said clamp bearing is fixed in connection with the outside surface of a screw ring on said manually tightened drill chuck, and the end surface of this clamp bearing is provided with at least one ratchet wheel slot; said resilient pawl is fixed on said ratchet wheel slot, and it includes a protuberance and a tooth piece; and said clip ring includes at least two arc segments that can mutually antagonistically snap onto the front end position of said main unit, the outer perimeter surface of this clip ring is fixed in connection with a front cap of said manually tightened drill chuck, said clip ring is connected with said clam

Abstract: The present invention publicly discloses a self-locking mechanism of a manually tightened drill chuck, including a ratchet wheel, a clamp bearing, at least one resilient pawl, and a clip ring, wherein said ratchet wheel is fixed in connection with the main unit of said manually tightened drill chuck, and on its back there are provided ratchet teeth facing the end surface of said main unit; said clamp bearing is fixed in connection with the outside surface of a screw ring on said manually tightened drill chuck, and the end surface of this clamp bearing is provided with at least one ratchet wheel slot; said resilient pawl is fixed on said ratchet wheel slot, and it includes a protuberance and a tooth piece; and said clip ring includes at least two arc segments that can mutually antagonistically snap onto the front end position of said main unit, the outer perimeter surface of this clip ring is fixed in connection with a front cap of said manually tightened drill chuck, said clip ring is connected with said clam

Abstract: The present invention generally relates to systems and methods for the production of high amounts of personalized interferons (IFNs), which are IFNs produced from the cells of the patient to whom the IFN is to be administered, for therapeutic and research uses. The system can also be used to produce high amounts of natural IFNs.