Patents by Inventor Luxin Feng

Luxin Feng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of inhibitors in reporter assays
    Patent number: 6284461
    Abstract: The present invention relates to methods for increasing the signal-to-noise ratio of an enzyme assay by contacting a sample comprising a membrane compartment with an inhibitor of an enzyme, contacting the sample with a substrate for the enzyme, and determining the activity of the enzyme. The method can be in a heterogeneous or homogeneous format. The methods of the present invention can be used for a variety of purposes, such as increasing the dynamic range of an enzyme assay, extending the useful loading time or assay measurement time of an enzyme assay, profiling the level of an enzyme in a sample, modulating the threshold activity of an enzyme assay, screening test compounds for activity, identifying modulators, identifying an inhibitor of an enzyme, and detecting membrane permeability. The present invention also relates to compounds useful in these methods.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: September 4, 2001
    Assignee: Aurora Biosciences Corporation
    Inventors: Gregor Zlokarnik, Luxin Feng