Patents by Inventor Luyao SHEN

Luyao SHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPLICATION OF APTAMER IN RECOGNITION AND BINDING OF ALKALINE PHOSPHATASE HETERODIMER OR TUMOR DETECTION
    Publication number: 20200362349
    Abstract: The present invention discloses the application of aptamer in recognition and binding of alkaline phosphatase heterodimer. The present invention provides an aptamer or its derivative, the nucleotide sequence of which is shown in SEQ ID NO: 1 in the sequence listing. The present invention also provides a kit including an aptamer or a derivative thereof, and a carrier for fixing or coupling the aptamer or a derivative thereof, wherein the aptamer is a single-stranded DNA molecule having the nucleotide sequence as shown in SEQ ID NO: 1. The method for capturing and detecting circulating tumor cells, exosomes and free alkaline phosphatase in peripheral blood highly expressing alkaline phosphatase based on the aptamer magnetic nanoparticle technology of the present invention can achieve highly selective capture and detection of target cells, exosomes or free proteins.
    Type: Application
    Filed: January 23, 2019
    Publication date: November 19, 2020
    Inventors: Dihua SHANGGUAN, Tao BING, Luyao SHEN, Xiangjun LIU, Nan ZHANG, Junyan WANG