Abstract: A system and method for treating migraine and headache through a digital therapeutic. The systems and methods described herein allow a migraine patient to manage symptoms, triggers, and therapeutic lifestyle interventions through an interconnected system, facilitated by a care team, to treat the root causes of migraine, and improve patient quality of life. The method includes collecting datasets associated with migraine, headache, migraine-related comorbidities, and lifestyle behavior at the mobile device to analyze neurological trigger patterns. Using the digital therapeutic application allows a patient to monitor and track lifestyle habits, to receive real time interventions, otherwise missed in traditional care settings, helping the patient learn lifestyle interventions that may mitigate future attacks. Given the complex nature of treating migraine, therapeutic lifestyle interventions are tailored to a patient's Neuroindividuality and facilitated by a care team.