Patents by Inventor Ly TU

Ly TU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12025592
    Abstract: A method for purifying exosomes from a cell culture medium comprising combining at least three (03) treating stages of a sample containing exosomes in the following specific order: (A) filtering the sample containing exosomes by tangential flow filtration (TFF) to obtain a TFF-filtered sample; (B) centrifuging the TFF-filtered sample by sucrose cushion centrifugation (SCC) to obtain a SCC-centrifuged sample; and (C) purifying the SCC-centrifuged sample by bind-elute size exclusion chromatography (BE-SEC) to obtain a purified exosomes. The present invention provides a comprehensive and efficient approach for purifying exosomes from a cell culture medium, facilitating using exosomes in various biomedical applications.
    Type: Grant
    Filed: August 21, 2023
    Date of Patent: July 2, 2024
    Assignee: NEXCALIBUR THERAPEUTICS, CORP.
    Inventor: Lan Ngoc Ly Tu
  • Patent number: 10071080
    Abstract: The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: September 11, 2018
    Assignees: MIFCARE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ PARIS-SUD 11
    Inventors: Gaël Jalce, Christophe Guignabert, Morane Le Hiress, Ly Tu, Bernardin Akagah
  • Publication number: 20170079958
    Abstract: The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.
    Type: Application
    Filed: May 18, 2015
    Publication date: March 23, 2017
    Inventors: Gaël JALCE, Christophe GUIGNABERT, Morane LE HIRESS, Ly TU, Bernardin AKAGAH