Patents by Inventor Lydie Meheus

Lydie Meheus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methylated, SmD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
    Publication number: 20020165355
    Abstract: The present invention relates to a method of producing certain peptides containing methylated arginines that are followed by a glycine residue and that constitute immunogenic determinants of antibodies present in sera from patients with systemic lupus erythematosus, or Epstein-Barr virus and wherein the methylation is a prerequisite for reacting with said antibodies. The invention also relates to the use of said peptides for diagnosis and treatment of systemic lupus erythematosus and related diseases, and diseases in which Epstein-Barr virus has been implicated.
    Type: Application
    Filed: January 24, 2002
    Publication date: November 7, 2002
    Applicant: INNOGENETICS N.V.
    Inventors: Lydie Meheus, Reinhard Georg Luhrmann, Ann Union, Joseph Raymackers
  • Peptides designed for the diagnosis and treatment of rheumatoid arthritis
    Publication number: 20020143143
    Abstract: The present invention relates to peptides that mimic the immunogenic determinants of self-proteins recognized by autoimmune antibodies in a biological sample from patients suffering from rheumatoid arthritis (RA). More particularly, the present invention relates to citrulline-containing peptides, which react with the majority of the latter antibodies. Furthermore, the present invention relates to diagnostic tools for a more convenient and sensitive diagnosis of RA and to therapeutic methods to treat RA.
    Type: Application
    Filed: December 21, 2000
    Publication date: October 3, 2002
    Inventors: Ann Union, Henri Moereels, Lydie Meheus
  • Methylated, SMD homologous peptides, reactive with the antibodies from sera of living beings affected with systemic lupus erythematosus
    Patent number: 6362007
    Abstract: The present invention relates to a method of producing certain peptides containing methylated arginines that are followed by a glycine residue and that constitute immunogenic determinants of antibodies present in sera from patients with systemic lupus erythematosus, or Epstein-Barr virus and wherein the methylation is a prerequisite for reacting with said antibodies. The invention also relates to the use of said peptides for diagnosis and treatment of systemic lupus erythematosus and related diseases, and diseases in which Epstein-Barr virus has been implicated.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: March 26, 2002
    Assignee: Innogenetics N.V.
    Inventors: Lydie Meheus, Ann Union, Joseph Raymackers, Reinhard Georg Lührmann