Patents by Inventor Lyle D. Isaacs

Lyle D. Isaacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-picornaviral ligands via a combinatorial computational and synthetic approach
    Publication number: 20020172942
    Abstract: The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.g., anti-picornaviral capsid-binding compounds.
    Type: Application
    Filed: May 21, 2002
    Publication date: November 21, 2002
    Applicant: President and Fellows of Harvard College
    Inventors: Diane M. Joseph-McCarthy, Lyle D. Isaacs, George M. Whitesides, Martin Karplus, James M. Hogle, James Li-wen Cheh
  • Anti-picornaviral ligands via a combinatorial computational and synthetic approach
    Patent number: 6416762
    Abstract: The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.g., anti-picornaviral capsid-binding compounds.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: July 9, 2002
    Assignee: President and Fellows of Harvard College
    Inventors: Diane M. Joseph-McCarthy, Lyle D. Isaacs, George M. Whitesides, Martin Karplus, James M. Hogle, James Li-wen Cheh