Patents by Inventor Lyle John Arnold, Jr.

Lyle John Arnold, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages
    Patent number: 6028188
    Abstract: Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: February 22, 2000
    Assignee: Genta Incorporated
    Inventors: Lyle John Arnold, Jr., Richard Isais Hogrefe, Mark Alan Reynolds, Timothy Andrew Riley, David Aaron Schwartz, Morteza Monir Vaghefi, Bob Dale Brown
  • Synthetic oligomers having phosphonate internucleosidyl linkages of undefined chirality mixed with non-phosphonate internucleosidyl linkages
    Patent number: 5986083
    Abstract: Oligomers having phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: November 16, 1999
    Assignee: Genta, Inc.
    Inventors: Brian P. Dwyer, Lyle John Arnold, Jr., Mark Alan Reynolds
  • Chirally enriched synthetic phosphate oligomers
    Patent number: 5955597
    Abstract: Oligomers having phosphonate internucleosidyl linkages which are enriched for phosphonate linkages of a preselected chirality which hybridize to an RNA target sequence and methods for their preparation are provided.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: September 21, 1999
    Assignee: Genta, Incorporated
    Inventors: Lyle John Arnold, Jr., Mark Alan Reynolds, Timothy Andrew Riley, David Aaron Schwartz, Morteza Monir Vaghefi
  • Compositions and methods of treatment of androgen-associated baldness using antisense oligomers
    Patent number: 5877160
    Abstract: Compositions and methods of treating androgen-associated hair loss, in particular decreasing the progression of male pattern baldness using a nucleoside Oligomer or Oligomers useful in the described methods are provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 2, 1999
    Assignee: Genta Incorporated
    Inventors: Mary Ellen Harper, Tod Mitchell Woolf, Lyle John Arnold, Jr.