Patents by Inventor Lyle Small

Lyle Small has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermochromic Temperature Sensor
    Publication number: 20200309607
    Abstract: A temperature sensor, and methods of making and using such a temperature sensor, whereby the temperature sensor includes a reversible thermochromic color-changing system having a dye, a developer, and a solvent. Upon exposure to a preselected temperature threshold, association or disassociation of the dye and the developer results in a visible color change. Further, the color-changing system includes a color-memory property which facilitates retention of the color change to effectively record exposure to the temperature threshold.
    Type: Application
    Filed: March 31, 2020
    Publication date: October 1, 2020
    Applicant: Chromatic Technologies, Inc.
    Inventors: Lyle Small, Timothy J. Owen, Ruizheng Wang, Medhanei Abraha
  • Method And Dyes For Detecting And Destroying Cancer Cells
    Publication number: 20180327427
    Abstract: This invention relates to new carbocyanine dye compositions, pharmaceutical compositions comprising such compositions, methods of detecting via near infrared fluorescent imaging incipient cancer cells and selective destruction of cancer cells identified by administration of such pharmaceutical compositions. A method of detecting and destroying cancer cells includes introducing a gold dye into an organism suspected of having a cancer cell. The gold dye is a carbocyanine dye covalently attached to a gold nanoparticle. A near infrared light is shined on a region suspected of having the cancer cell. Fluorescence from the gold dye is detected. A beam of radio frequency energy is directed at the region to induce hyperthermia in the cancer cell. The carbocyanine dye has the most basic structure of MHI-148 and structures 6 and 22 with a Aun—[S—CH2(CH2)9CH2—(OCH2CH2)4O]COCH2CH2-phenyl-O group on a cyclohexene ring that imparts activity to the cancer cell binding and destruction processes.
    Type: Application
    Filed: July 23, 2018
    Publication date: November 15, 2018
    Applicant: Lahjavida, LLC
    Inventors: James J. Krutak, Lyle Small, Maged Henary, Gabor Patonay
  • Method and dyes for detecting and destroying cancer cells
    Patent number: 10030036
    Abstract: This invention relates to new carbocyanine dye compositions, pharmaceutical compositions comprising such compositions, methods of detecting via near infrared fluorescent imaging incipient cancer cells and selective destruction of cancer cells identified by administration of such pharmaceutical compositions. A method of detecting and destroying cancer cells includes introducing a gold dye into an organism suspected of having a cancer cell. The gold dye is a carbocyanine dye covalently attached to a gold nanoparticle. A near infrared light is shined on a region suspected of having the cancer cell. Fluorescence from the gold dye is detected. A beam of radio frequency energy is directed at the region to induce hyperthermia in the cancer cell. The carbocyanine dye has the most basic structure of MHI-148 and structures 6 and 22 with a Aun—[CH2(CH2)9CH2—(OCH2CH2)4O]COCH2CH2-phenyl-O group on a cyclohexene ring that imparts activity to the cancer cell binding and destruction processes.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: July 24, 2018
    Assignee: Lahjavida, LLC
    Inventors: James J. Krutak, Lyle Small, Maged Henary, Gabor Patonay
  • Yellow thermochromic dyes, inks composition and level indicators
    Patent number: 9745487
    Abstract: A new leuco dye produces a yellow color while demonstrating also exceptional light and thermal stability under light.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: August 29, 2017
    Assignee: Chromatic Technologies, Inc.
    Inventors: Ruizheng Wang, Yu Du, Timothy J. Owen, Medhanei Abraha, Terrill Scott Clayton, Lyle Small
  • Small scale microencapsulated pigments and uses thereof
    Patent number: 9695320
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: July 4, 2017
    Assignee: Chromatic Technologies, Inc.
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small
  • Yellow Thermochromic Dyes, Inks Composition And Level Indicators
    Publication number: 20160333210
    Abstract: A new leuco dye produces a yellow color while demonstrating also exceptional light and thermal stability under light.
    Type: Application
    Filed: July 25, 2016
    Publication date: November 17, 2016
    Applicant: Chromatic Technologies, Inc.
    Inventors: Ruizheng Wang, Yu Du, Timothy J. Owen, Medhanei Abraha, Terrill Scott Clayton, Lyle Small
  • Yellow thermochromic dyes, inks composition and level indicators
    Patent number: 9399716
    Abstract: A new leuco dye produces a yellow color while demonstrating also exceptional light and thermal stability under light.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: July 26, 2016
    Assignee: Chromatic Technologies Inc.
    Inventors: Ruizheng Wang, Yu Du, Timothy J. Owen, Medhanei Abraha, Terrill Scott Clayton, Lyle Small
  • Small Scale Microencapsulated Pigments And Uses Thereof
    Publication number: 20160083586
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 24, 2016
    Applicant: Chromatic Technologies, Inc.
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small
  • METHOD AND DYES FOR DETECTING AND DESTROYING CANCER CELLS
    Publication number: 20150376209
    Abstract: This invention relates to new carbocyanine dye compositions, pharmaceutical compositions comprising such compositions, methods of detecting via near infrared fluorescent imaging incipient cancer cells and selective destruction of cancer cells identified by administration of such pharmaceutical compositions. A method of detecting and destroying cancer cells includes introducing a gold dye into an organism suspected of having a cancer cell. The gold dye is a carbocyanine dye covalently attached to a gold nanoparticle. A near infrared light is shined on a region suspected of having the cancer cell. Fluorescence from the gold dye is detected. A beam of radio frequency energy is directed at the region to induce hyperthermia in the cancer cell. The carbocyanine dye has the most basic structure of MHI-148 and structures 6 and 22 with a Aun—[CH2(CH2)9CH2—(OCH2CH2)4O]COCH2CH2-phenyl-O group on a cyclohexene ring that imparts activity to the cancer cell binding and destruction processes.
    Type: Application
    Filed: May 12, 2010
    Publication date: December 31, 2015
    Inventors: JAMES J. KRUTAK, Lyle Small, Maged Henary, Gabor Patonay
  • Small scale microencapsulated pigments and uses thereof
    Patent number: 9175175
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: November 3, 2015
    Assignee: Chromatic Technologies, Inc.
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small
  • SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF
    Publication number: 20150076423
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Application
    Filed: October 16, 2014
    Publication date: March 19, 2015
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small
  • YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS
    Publication number: 20150018441
    Abstract: A new leuco dye produces a yellow color while demonstrating also exceptional light and thermal stability under light.
    Type: Application
    Filed: July 2, 2014
    Publication date: January 15, 2015
    Inventors: Ruizheng Wang, Yu Du, Timothy J. Owen, Medhanei Abraha, Terrill Scott Clayton, Lyle Small
  • Small scale microencapsulated pigments and uses thereof
    Patent number: 8883049
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: November 11, 2014
    Assignee: Chromatic Technologies, Inc.
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small
  • SMALL SCALE MICROENCAPSULATED PIGMENTS AND USES THEREOF
    Publication number: 20140272161
    Abstract: A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: CHROMATIC TECHNOLOGIES, INC.
    Inventors: Terrill Scott Clayton, Timothy J. Owen, Lyle Small