Patents by Inventor Lyn Oligino

Lyn Oligino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and uses thereof for identifying and targeting provasopressin-expressing cancer cells
    Patent number: 7790162
    Abstract: The present invention discloses antibodies, antigen binding fragments, peptides and peptidomimetics immunoreactive with provasopressin and compositions thereof, methods of phenotyping tissue samples, methods of treating cancer, and kits for phenotyping test biopsy samples and bodily fluids for breast cancer, small cell lung cancer, ductal carcinoma in situ, and atypical ductal hyperplasia.
    Type: Grant
    Filed: July 16, 2003
    Date of Patent: September 7, 2010
    Assignee: Woomera Therapeutics, Inc.
    Inventors: William G. North, Brendan P. Keegan, Lyn Oligino
  • Compositions And Uses Thereof For Identifying And Targeting Provasopressin-Expressing Cancer Cells
    Publication number: 20080050376
    Abstract: The present invention discloses antibodies, antigen binding fragments, peptides and peptidomimetics immunoreactive with provasopressin and compositions thereof, methods of phenotyping tissue samples, methods of treating cancer, and kits for phenotyping test biopsy samples and bodily fluids for breast cancer, small cell lung cancer, ductal carcinoma in situ, and atypical ductal hyperplasia.
    Type: Application
    Filed: July 16, 2003
    Publication date: February 28, 2008
    Inventors: William G. North, Brendan P. Keegan, Lyn Oligino
  • Methods and compositions for inhibiting GRB7
    Patent number: 7229960
    Abstract: The invention provides methods and compositions for treating subjects using Grb7 antagonists. Specifically disclosed are Grb7 antagonists that bind selectively to Grb7 and interfere with the ability of Grb7 to bind to its native ligands. These compositions are useful in the prevention and treatment of disorders characterized by abnormal interaction of Grb7 with its native ligands (e.g., ErbB2).
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: June 12, 2007
    Assignee: University of Vermont and State Agricultural College
    Inventors: Stephanie C. Pero, David N. Krag, Lyn Oligino
  • Binding peptides specific for the extracellular domain of ErbB2 and uses therefor
    Publication number: 20060276379
    Abstract: The invention provides methods and compositions for diagnosing and treating subjects using EBPs. Specifically disclosed are peptides and peptidomimetics that bind selectively to the extracellular domain of ErbB2. These compositions are useful in the prevention and treatment of disorders characterized by ErbB2 overexpression (e.g., breast cancer).
    Type: Application
    Filed: August 10, 2006
    Publication date: December 7, 2006
    Applicant: University of Vermont and State Agricultural College
    Inventors: David Krag, Stephanie Pero, Lyn Oligino
  • Binding peptides specific for the extracellular domain of ErbB2 and uses therefor
    Patent number: 7098302
    Abstract: The invention provides methods and compositions for diagnosing and treating subjects using EBPs. Specifically disclosed are peptides and peptidomimetics that bind selectively to the extracellular domain of ErbB2. These compositions are useful in the prevention and treatment of disorders characterized by ErbB2 overexpression (e.g., breast cancer).
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: August 29, 2006
    Assignee: University of Vermont and State Agricultural College
    Inventors: David N. Krag, Stephanie C. Pero, Lyn Oligino
  • Binding peptides specific for the extracellular domain of ErbB2 and uses therefor
    Publication number: 20030216309
    Abstract: The invention provides methods and compositions for diagnosing and treating subjects using EBPs. Specifically disclosed are peptides and peptidomimetics that bind selectively to the extracellular domain of ErbB2. These compositions are useful in the prevention and treatment of disorders characterized by ErbB2 overexpression (e.g., breast cancer).
    Type: Application
    Filed: October 15, 2002
    Publication date: November 20, 2003
    Applicant: University of Vermont and State Agricultural College
    Inventors: David N. Krag, Stephanie C. Pero, Lyn Oligino
  • Methods and compositions for inhibiting GRB7
    Publication number: 20030105000
    Abstract: The invention provides methods and compositions for treating subjects using Grb7 antagonists. Specifically disclosed are Grb7 antagonists that bind selectively to Grb7 and interfere with the ability of Grb7 to bind to its native ligands. These compositions are useful in the prevention and treatment of disorders characterized by abnormal interaction of Grb7 with its native ligands (e.g., ErbB2).
    Type: Application
    Filed: November 5, 2001
    Publication date: June 5, 2003
    Inventors: Stephanie C. Pero, David N. Krag, Lyn Oligino