Patents by Inventor Lyna LUO

Lyna LUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132887
    Abstract: Disclosed herein are, inter alia, inhibitors of protein arginine methyltransferase 9 and pharmaceutical compositions thereof, and methods comprising the use of protein arginine methyltransferase 9 inhibitors for the treatment of a protein arginine methyltransferase 9-modulated disease or disorder, such as a hematological cancer.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 25, 2024
    Applicants: City of Hope, Western University of Health Sciences
    Inventors: Ling Li, Haojie Dong, Lei Zhang, Xin He, Yun Lyna Luo, Yi-Chun Lin
  • Publication number: 20190030114
    Abstract: Molecules that selectively inhibit or stimulate the activity of isoforms of calpains are presented. Methods for screening and characterizing such molecules are also presented. Specific functions of calpain-1 calpain-2 in long term potentiation (LTP), learning and memory, neurodegeneration and diseases of synaptic dysfunction are characterized using novel calpain inhibitors, substrates and related methods. The compounds, compositions, and methods described herein are expected to be useful, for treating neurodegenerative diseases and other diseases of synaptic function, and for modulating cognition in patients in need thereof.
    Type: Application
    Filed: November 11, 2015
    Publication date: January 31, 2019
    Applicant: WESTERN UNIVERSITY OF HEALTH SCIENCES
    Inventors: Michel BAUDRY, Xiaoning BI, Steve STANDLEY, Lyna LUO, Yubin WANG, Guoqi ZHU, Victor BRIZ