Patents by Inventor Lynda E. Misher

Lynda E. Misher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130052195
    Abstract: The present disclosure relates to compositions and methods for treating autoimmune diseases including rheumatoid arthritis. In particular, the present disclosure relates to compositions comprising IL-6 antagonists (e.g., anti-IL6 or anti-IL6R or anti-hyperIL6) and TNF-? antagonists (e.g., (anti-TNF or etanercept) and methods of using same in the treatment of rheumatoid arthritis.
    Type: Application
    Filed: December 23, 2010
    Publication date: February 28, 2013
    Applicant: Emergent Product Development Seattle,LLC
    Inventors: Lynda E. Misher, Alan Keith Lofquist
  • Patent number: 7241876
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: July 10, 2007
    Assignee: Corixa Corporation
    Inventors: Tony N. Frudakis, Steven G. Reed, John M. Smith, Lynda E. Misher, Davin C. Dillon, Marc W. Retter, Aijun Wang, Yasir A. W. Skeiky, Susan L. Harlocker, Craig H. Day, Samuel X. Li, Ta Deng
  • Patent number: 6861506
    Abstract: Compositions and methods for the detection and therapy of breast cancer are disclosed. The compounds provided include nucleotide sequences that are preferentially expressed in breast tumor tissue, as well as polypeptides encoded by such nucleotide sequences. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for the prevention and treatment of breast cancer. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring the progression of breast cancer in a patient.
    Type: Grant
    Filed: March 23, 2000
    Date of Patent: March 1, 2005
    Assignee: Corixa Corporation
    Inventors: Tony N. Frudakis, John M. Smith, Steven G. Reed, Lynda E. Misher, Marc W. Retter, Davin C. Dillon
  • Patent number: 6828431
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: December 7, 2004
    Assignee: Corixa Corporation
    Inventors: Tony N. Frudakis, Steven G. Reed, John M. Smith, Lynda E. Misher, Davin C. Dillon, Marc W. Retter, Aijun Wang, Yasir A. W. Skeiky, Susan L. Harlocker
  • Publication number: 20040073016
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: February 20, 2002
    Publication date: April 15, 2004
    Applicant: Corixa Corporation
    Inventors: Tony N. Frudakis, Steven G. Reed, John M. Smith, Lynda E. Misher, Davin C. Dillon, Marc W. Retter, Aijun Wang, Yasir A.W. Skeiky, Susan L. Harlocker, Craig H. Day, Samuel X. Li, Ta Deng
  • Publication number: 20020165371
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: August 7, 2001
    Publication date: November 7, 2002
    Inventors: Tony N. Frudakis, Steven G. Reed, John M. Smith, Lynda E. Misher, Davin C. Dillon, Marc W. Retter, Aijun Wang, Yasir A.W. Skeiky, Susan L. Harlocker, Craig H. Day, Samuel X. Li, Ta Deng
  • Publication number: 20020068285
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Application
    Filed: March 16, 2001
    Publication date: June 6, 2002
    Inventors: Tony N. Frudakis, Steven G. Reed, John M. Smith, Lynda E. Misher, Davin C. Dillon, Marc W. Retter, Aijun Wang, Yasir A. W. Skeiky, Susan L. Harlocker, Craig H. Day