Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Abstract: The invention provides particles, compositions including the particles, and methods of making the particles using electrospray. In certain embodiments, the particles allow for high concentrations of a therapeutic or diagnostic agent to be delivered at low viscosity. Particles may also exhibit beneficial properties with respect to stability.

Abstract: Systems and methods of laying out integrated circuits are disclosed. During the layout stage of an integrated circuit device, a fixed, physical geometry is created of the parameterized cells (PCells) included in the integrated circuit schematic. The systems include a proxy engine configured to save to cache the geometries created during the layout stage such that the geometries need not be recomputed when the design is opened after a save to disk operation, during which geometries may otherwise be destroyed. The proxy engine may further be configured to delegate requests for the creation of geometries to other components of the integrated circuit design system. In addition, the proxy engine may be configured to perform customized evaluations of PCells, other than or in addition to caching and delegation.

Abstract: A switch for use with an electrosurgical tool having a heatable tip connectable to a power source and a suction passage connectable to a suction source. The switch comprises a main body having a suction passage extending therethrough connectable to the suction passage of the tool. A cavity in the main body intersects the suction passage and is adapted to slidably receive a mounting post to permit slidable movement of the main body over the mounting post. The mounting post has an end protruding from the main body that is pivotally connectable to the tool. An opening extends through the mounting post that is alignable with the suction passage. In operation, the main body of the switch is manually movable between a default position in which the suction passage and the opening are misaligned to block suction and an operating position in which the suction passage and opening are aligned to permit suction.