Patents by Inventor Lynn Cook Winterton
Lynn Cook Winterton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6589665Abstract: The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having attached to its surface at least one polyionic material that comprises covalently bound initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic monomers or macromonomers to the bulk material surface provided with the initiator radicals and polymerizing said monomers or macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.Type: GrantFiled: May 30, 2001Date of Patent: July 8, 2003Assignee: Novartis AGInventors: Peter Chabrecek, Dieter Lohmann, Jörg Leukel, Lynn Cook Winterton, Yongxing Qiu, John Martin Lally
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Publication number: 20030117579Abstract: The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The antimicrobial coating on the medical device of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial, a low toxicity, low coefficient of friction, and increased hydrophilicity while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial coating thereon.Type: ApplicationFiled: November 4, 2002Publication date: June 26, 2003Inventors: Carol Ann Morris, Manal M. Gabriel, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Marcia Kay Ash, Fiona Patricia Carney, Courtney Flem Morgan
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Publication number: 20030065051Abstract: Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic material, rinsing and drying. The coating process may be applied a plurality of times to achieve a multi-layer coating on the lens surface. A particularly preferred embodiment is a contact lens comprising a highly oxygen permeable hydrophobic core coated with a 5 to 20 bilayers of hydrophilic polyionic materials.Type: ApplicationFiled: July 24, 2002Publication date: April 3, 2003Inventors: Lynn Cook Winterton, Juergen Vogt, John Martin Lally, Friedrich Stockinger
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Publication number: 20030039742Abstract: The present invention provides a method for forming on a medical device, preferably an ophthalmic lens, more preferably a contact lens, a diffusion-controllable coating capable of controlling the out-diffusion or release of guest materials from the medical device. The method of the invention comprises: (1) applying one layer of clay and optionally one or more layers of polyionic materials onto the medical device; or (2) applying alternatively a layer of a first polyionic material and a layer of a second polyionic material having charges opposite of the charges of the first polyionic material onto the medical device and releasing the coated medical device into a releasing medium having a composition capable of imparting a desired permeability to the diffusion-controllable coating on the medical device.Type: ApplicationFiled: May 22, 2002Publication date: February 27, 2003Inventors: Yongxing Qiu, Fiona Patricia Carney, Nichola Kotov, John Martin Lally, Carol Ann Morris, Lynn Cook Winterton
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Publication number: 20030024829Abstract: An embodiment of the invention is a basket for holding ophthalmic lenses. A basket of the present invention has a lattice structure having a lens contacting side and an opposite lens non-contacting side, wherein the lens-contacting side of the lattice has a very sharp edge structure and the lens non-contacting side can be a normal solid surface to maintain the mechanical strength of the basket. A tray that comprises a plurality of baskets is another embodiment of the invention. In addition, the invention provides a stack assembly that comprises a plurality of trays each of which comprises a plurality of baskets.Type: ApplicationFiled: May 22, 2002Publication date: February 6, 2003Inventors: Yasuo Matsuzawa, Lynn Cook Winterton, Michael Nelson Wilde, Joseph Michael Thurber
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Publication number: 20030012872Abstract: This invention provides a method for efficiently applying a coating to each of a plurality of objects selected from the group consisting of ophthalmic lenses, molds for making ophthalmic lenses, and other medical devices, the method comprising dipping the plurality of objects into a coating bath containing a coating solution having a coating material; and creating with a means a convective current flow and thereby forcing a coating solution flowing over and under each of the plurality of ophthalmic lenses. In a preferred embodiment, the plurality of objects are held in baskets which are pre-conditioned to have a first layer of polyelectrolytes and a second layer of aqueous solution or have a mixed layer of polyelectrolytes and aqueous solution on the surfaces of the baskets.Type: ApplicationFiled: May 22, 2002Publication date: January 16, 2003Inventors: Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Yasuo Matsuzawa, Rafael Victor Andino, Allen Gilliard
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Publication number: 20030008154Abstract: An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: ApplicationFiled: May 22, 2002Publication date: January 9, 2003Inventors: Celeste Aguado, Paul Clement Nicolson, Lynn Cook Winterton, Yongxing Qiu, John Martin Lally, Jacalyn Mary Schremmer
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Publication number: 20020182316Abstract: The invention provide a method for applying a coating to an ophthalmic lens or a mold for making the ophthalmic lens or a medical device other than ophthalmic lens. The method comprises spraying at least one layer of a coating liquid onto an ophthalmic lens using a spraying process selected from the group consisting of an air-assisted atomization and dispensing process, an ultrasonic-assisted atomization and dispensing process, a piezoelectric assisted atomization and dispensing process, an electro-mechanical jet printing process, a piezo-electric jet printing process, a piezo-electric with hydrostatic pressure jet printing process, and a thermal jet printing process. The coating can comprise a property/functionality pattern or a color image or combination of both.Type: ApplicationFiled: May 22, 2002Publication date: December 5, 2002Inventors: Allen Gilliard, Lynn Cook Winterton, Rafael Victor Andino, John Lally
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Patent number: 6451871Abstract: Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, followed by spray coating a polyanionic material, rinsing and drying. The coating process may be applied a plurality of times to achieve a multi-layer coating on the lens surface. A particularly preferred embodiment is a contact lens comprising a highly oxygen permeable hydrophobic core coated with a 5 to 20 bilayers of hydrophilic polyionic materials.Type: GrantFiled: April 27, 2000Date of Patent: September 17, 2002Assignee: Novartis AGInventors: Lynn Cook Winterton, Juergen Vogt, John Martin Lally, Friedrich Stockinger
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Publication number: 20020086160Abstract: The invention relates to a process for coating a material surface, comprising the steps of:Type: ApplicationFiled: August 24, 2001Publication date: July 4, 2002Inventors: Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Paul Pasic, Hans Griesser, Peter Kambouris, Peter Chabrecek
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Publication number: 20020025389Abstract: A system and method for treating the surface of an optical lens is provided. A predetermined pressure and a plasma gas are maintained in a coating chamber. A plasma cloud of gas is established between electrodes in the chamber. An entry chamber is upstream from the coating chamber, and an exit chamber is disposed downstream from the chamber. A lens is moved into the entry chamber, and at least a portion of the entry chamber adjacent to the coating chamber is brought to the predetermined pressure. Process gas is introduced into this area. The entry chamber is then brought into communication with the coating chamber, and the lens is moved into the coating chamber and through the cloud. Process gas is introduced into at least a portion of the exit chamber adjacent the coating chamber, and this portion is brought to the predetermined pressure. The lens is then moved from the coating chamber to the exit chamber.Type: ApplicationFiled: July 23, 2001Publication date: February 28, 2002Inventors: Yasuo Matsuzawa, Lynn Cook Winterton
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Publication number: 20020006493Abstract: The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having attached to its surface at least one polyionic material that comprises covalently bound initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic monomers or macromonomers to the bulk material surface provided with the initiator radicals and polymerizing said monomers or macromonomers.Type: ApplicationFiled: May 30, 2001Publication date: January 17, 2002Inventors: Peter Chabrecek, Dieter Lohmann, Jorg Leukel, Lynn Cook Winterton, Yongxing Qiu, John Martin Lally
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Publication number: 20010048975Abstract: A method of forming a coating of polyionic materials in a layer-by-layer-like manner onto a polymeric material is provided. A polymeric material, such as a contact lens, can be dipped once into a solution of polyionic materials such that layers of polyionic material can be formed thereon. A single dip solution of the present invention typically contains a polyanionic material and a polycationic material in a non-stoichiometric amount and maintained within a certain pH range.Type: ApplicationFiled: February 1, 2001Publication date: December 6, 2001Inventors: Lynn Cook Winterton, John Martin Lally, Michael Rubner, Yongxing Qiu
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Publication number: 20010045676Abstract: A method of forming a contact lens within a mold is provided. A coating of a polyionic material(s) is applied to the mold before forming a lens therein. The coating can be applied by spraying or dipping the mold within a solution(s) of polyionic materials. Various other additives can also be applied to the mold. The coating can then be transferred to a contact lens formed within the mold such that the resulting lens has altered surface properties.Type: ApplicationFiled: January 31, 2001Publication date: November 29, 2001Inventors: Lynn Cook Winterton, Yongxing Qiu, John Martin Lally, Paul Clement Nicolson
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Patent number: 5965631Abstract: An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: GrantFiled: July 1, 1998Date of Patent: October 12, 1999Assignees: CIBA Vision Corporation, Commonwealth Scientific and Industrial Research OrganisationInventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
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Patent number: 5849811Abstract: An ophthalmic lens suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: GrantFiled: July 17, 1996Date of Patent: December 15, 1998Assignees: CIBA Vision Corporation, The Commonwealth of Australia Commonwealth Scientific and Industrial Research OrganizationInventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
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Patent number: 5789461Abstract: An ophthalmic lens suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: GrantFiled: July 18, 1996Date of Patent: August 4, 1998Assignee: Ciba Vision CorporationInventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy S. Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
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Patent number: 5776999Abstract: An ophthalmic lens screening method suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: GrantFiled: July 17, 1996Date of Patent: July 7, 1998Assignee: CIBA Vision CorporationInventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
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Patent number: 5760100Abstract: An ophthalmic lens suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.Type: GrantFiled: December 8, 1995Date of Patent: June 2, 1998Assignees: CIBA Vision Corporation, Commonwealth Scientific and Industrial Research OrganisationInventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton