Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human PAR-2 and compositions comprising such antibodies or antigen-binding fragments thereof. In a particular aspect, the antibodies or antigen-binding fragments thereof that specifically bind to human PAR-2 block the interaction between a PAR-2 activating ligand and an extracellular domain of PAR-2, and/or blocks PAR-2 activation by a PAR-2 activating ligand, In further aspects, the antibodies or antigen-binding fragments can be used to treat diseases or conditions associated with increased expression of PAR-2 and/or diseases or conditions that can be alleviated by antagonizing activation of PAR-2 by a PAR-2 activating ligand (e.g., airway diseases, skin diseases, cancer, orofacial granulomatosis, inflammatory conditions, and pain associated with various diseases or conditions).

Abstract: A method and apparatus for stopping an AC motor that is controlling a load while detecting mechanical brake slippage of a mechanical brake for holding the load against movement includes a controller for decreasing torque-producing current commands from the drive while a speed regulator is commanding zero speed, sensing movement of the load while the speed regulator is commanding zero speed, detecting movement of the load past a pre-determined distance limit, and increasing torque to support the load and prevent further movement of the load. The controller will again decrease torque-producing current commands from the drive, and again checking for movement of the load, and upon sensing no load movement upon reaching zero torque, then shutting off the motor.