Abstract: Methods of improving subjective sleep efficiency, reducing subjective sleep onset latency, and/or reducing subjective wake after sleep onset in subjects comprising administering to the subject 5 mg or 10 mg of lemborexant or an equivalent dose of a pharmaceutically acceptable salt thereof are disclosed herein. Also disclosed herein is lemborexant or a pharmaceutically acceptable salt thereof for use in improving subjective sleep efficiency, reducing subjective sleep onset latency, and/or reducing subjective wake after sleep onset in a subject comprising administering to the subject 5 mg or 10 mg of lemborexant or an equivalent dose of a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are methods of reducing clinical decline in a subject having early Alzheimer's disease, methods of converting an amyloid positive subject having early Alzheimer's disease to amyloid negative, methods of reducing brain amyloid level in a subject, and methods of preventing Alzheimer's disease, the methods comprising administering a composition comprising a therapeutically effective amount of at least one anti-A? protofibril antibody. In some embodiments, the subject is ApoE4-positive. In some embodiments, the at least one anti-A? protofibril antibody is BAN2401.

Abstract: A nematic bistable liquid crystal (LC) display element includes a substrate having an inner surface alignment layer and a pair of in-plane electrodes in proximity to the substrates. The display element has charged electrophoretic nanoparticles in the LC medium configured to setup a matrix with the LC when an electric field is applied to the electrodes.

Abstract: A method forms a first inorganic dielectric layer having a first concentration of defects and a second inorganic dielectric layer in contact with a first layer and having a second lesser concentration of defects.

Abstract: A method forms a first inorganic dielectric layer having a first concentration of defects and a second inorganic dielectric layer in contact with a first layer and having a second lesser concentration of defects.

Abstract: An apparatus and method relating to a first inorganic dielectric layer having a first concentration of defects and a second inorganic dielectric layer in contact with a first layer and having a second lesser concentration of defects are disclosed.

Abstract: A nematic bistable liquid crystal (LC) display element includes a substrate having an inner surface alignment layer and a pair of in-plane electrodes in proximity to the substrates. The display element has charged electrophoretic nanoparticles in the LC medium configured to setup a matrix with the LC when an electric field is applied to the electrodes.

Abstract: An apparatus and method relating to a first inorganic dielectric layer having a first concentration of defects and a second inorganic dielectric layer in contact with a first layer and having a second lesser concentration of defects are disclosed.

Abstract: A method and apparatus for remote administration of programmable workstations coupled to a host computer in a data processing system. Master user configuration files are established and stored in association with a host computer for selected programmable workstations, each including a desired or existing configuration for an associated programmable workstation. At least one user within the data processing system is designated as a system administrator and permitted to selectively alter particular master user configuration files. Thereafter, the altered master user configuration file is automatically copied to an associated programmable workstation, in response to an initiation of communication between the programmable workstation and the host computer, altering the configuration of that workstation.