Patents by Inventor Lynne D. Keyes

Lynne D. Keyes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and materials for producing soluble biological mediators from white blood cells
    Patent number: 4591557
    Abstract: A process and cellular system for producing soluble biological mediators, including cytokines, lymphokines, monokines and interferons, and mRNA therefor, from white blood cells is provided. The process involves treating white blood cells with a mitogenic or antigenic agent in the presence of a controlled amount of red blood cells. Increases in production of the soluble biological mediator, gamma interferon, on the order of 5 to 10 fold have been achieved by maintaining the ratio of red blood cells to white blood cells between 10 to 1 and about 50 to 1. The process is particularly useful in producing HuIFN-.gamma. with PHA-P.
    Type: Grant
    Filed: December 2, 1982
    Date of Patent: May 27, 1986
    Assignee: Interferon Sciences, Inc.
    Inventors: Lynne D. Keyes, Douglas Testa