Patents by Inventor Lynne Krummen

Lynne Krummen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies with altered effector functions
    Publication number: 20070269371
    Abstract: The invention provides antibodies with altered effector functions, and methods of using these antibodies in the treatment of various diseases. The invention further provides compositions, kits and articles of manufacture for practicing methods of the invention.
    Type: Application
    Filed: February 28, 2007
    Publication date: November 22, 2007
    Inventors: Lynne Krummen, Dorothea Reilly, Stefanie Weikert
  • Expression Vectors and Methods
    Publication number: 20070054303
    Abstract: Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.
    Type: Application
    Filed: September 25, 2006
    Publication date: March 8, 2007
    Applicant: Genentech, Inc.
    Inventors: Vanessa Chisholm, Craig Crowley, Lynne Krummen, Yu-Ju Meng, Amy Shen
  • Expression Vectors and Methods
    Publication number: 20070037254
    Abstract: Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.
    Type: Application
    Filed: September 25, 2006
    Publication date: February 15, 2007
    Applicant: Genentech, Inc.
    Inventors: Vanessa Chisholm, Craig Crowley, Lynne Krummen, Yu-Ju Meng
  • Antibodies with altered effector functions
    Publication number: 20050152894
    Abstract: The invention provides antibodies with altered effector functions, and methods of using these antibodies in the treatment of various diseases. The invention further provides compositions, kits and articles of manufacture for practicing methods of the invention.
    Type: Application
    Filed: September 3, 2004
    Publication date: July 14, 2005
    Inventors: Lynne Krummen, Dorothea Reilly, Stefanie Weikert
  • Intron fusion construct and method of using for selecting high-expressing production cell lines
    Publication number: 20050019925
    Abstract: This invention relates to a DNA construct, methods of selecting for high-expressing host cells, a method of producing a protein of interest in high yields and a method of producing eukaryotic cells having multiple copies of a sequence encoding a protein of interest. In one method, stable clones capable of producing a high level of a product of interest are generated from one step of a direct selection immediately after transfection.
    Type: Application
    Filed: November 14, 2003
    Publication date: January 27, 2005
    Applicant: Genentech, Inc.
    Inventors: Lynne Krummen, Amy Shen, Vanessa Chisholm
  • Expression vectors and methods
    Publication number: 20050005310
    Abstract: Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.
    Type: Application
    Filed: November 14, 2003
    Publication date: January 6, 2005
    Inventors: Vanessa Chisholm, Craig Crowley, Lynne Krummen, Yu-Ju Meng, Amy Shen
  • GLYCOPROTEIN PRODUCTION PROCESS
    Publication number: 20020045207
    Abstract: Glycoprotein production methods and host cell lines are provided. The production methods and host cells include the functional expression of a galactosyltransferase and a sialyltransferase alone or in combination with a host cell line selected for lack of functional expression of a glycohydrolytic enzyme such as a sialidase.
    Type: Application
    Filed: October 19, 1998
    Publication date: April 18, 2002
    Inventors: LYNNE A. KRUMMEN, MARY B. SLIWKOWSKI, TOM WARNER