Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be configured to extend radially outwardly as the spacer body extends away from the distal end toward the proximal end. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

Abstract: The present disclosure relates to compositions and methods for treating a wound, or location of interest, in a subject by topically administering to the subject a therapeutic composition of the present disclosure. The composition of the disclosure comprises nanoparticle (NP) composites for delivering at least two cargos to the wound. In certain embodiments, the at least two cargos comprise a metal and a small molecule drug.

Abstract: A method performed by a wireless transmit/receive unit (WTRU) may include sending, to a network, a registration message indicating the WTRU is capable of device-to-device (D2D) communication and sending a request for assistance in discovering at least one other WTRU in proximity to the WTRU. The method may include receiving, from the network, in response to the request for assistance in discovering the at least one other WTRU, assistance information including one or more of a unique identifier or filtering information. The method may include performing, using the assistance information, a device discovery procedure to discover the at least one other WTRU, wherein the device discovery procedure comprises at least one of: monitoring for signals from the at least one other WTRU using the assistance information, or sending a discovery announcement based on the assistance information and transmitting application data directly to the at least one other WTRU.

Abstract: The invention provides a plurality of display devices such as hand dryers, each with a programmed computer display, and all communicating to a central location via a high speed link system. A display screen is mounted to each of the hand dryers and viewable by a user while drying the user's hands. A processor is located within the housing and is in signal-communication with the display screen. The high-speed link system is in signal-communication with each processor and an external data source, wherein the data source communicates with the processor to change the image displayed on the display screen. Sensors communicate ambient conditions outside of the display screen to a database.

Abstract: A method and apparatus are described for supporting a two-stage device-to-device (D2D) discovery using a D2D interworking function (IWF). A D2D IWF component may be configured to perform mapping between an application running on an application server and a third generation partnership project (3GPP) network, and provide a set of application programming interfaces (APIs) to allow discovery to be provided as a service to D2D applications. An application identifier may be mapped to a 3GPP identifier. Further, a method and apparatus are described for performing client-server discovery. A first wireless transmit/receive unit (WTRU) may be configured for a listen-only operation, and a second WTRU may be configured to transmit beacons. The first and second WTRUs may perform a radio access network (RAN) discovery procedure at an access stratum (AS) layer. A method and apparatus for performing charging for D2D service using a D2D IWF are also described.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: Disclosed herein is a topical composition that treats and reduces the visual appearance of a scar through the combination of a hydrophilic occlusion forming agent (e.g., having a water solubility of more than about 75%, such as glycerin) with one or more proteolytic enzymes and an antioxidant system that includes polyphenol antioxidants (e.g., green tea polyphenols). Also disclosed herein are methods of administering the topical compositions described herein for treating and/or reducing the visual appearance of a scar by themselves or as part of a scar treatment regimen in combination with a variety of dermatological procedures. Processes of preparing the topical compositions disclosed herein are also described in certain embodiments.

Abstract: Disclosed in certain embodiments are skincare formulations and treatment methods having hyaluronic acid, or its associated salts, and one or more of ascorbic acid, glycolic acid or lactic acid. In certain embodiments, the formulations and treatments are applied to the skin during and/or before and/or after dermatological procedures that affect the skin's barrier for alleviating patient discomfort and enabling rapid healing of irritated and damaged skin.

Abstract: Disclosed in certain embodiments herein is a formulation including a plant-based growth factor and at least one of a peptide, an antioxidant and a botanical agent. The formulation has been found to improve the properties of the skin on the face and on areas under the eye. Also disclosed herein are methods of administering the formulation described herein for treating a skin.

Abstract: A cup holder assembly includes a body that defines a cup-receiving cavity and an aperture that extends through a side wall of the body, a first bracing feature and a second bracing feature, each of which is coupled to the body and positioned outside of the cup-receiving cavity, and a retention finger. The retention finger includes a first portion that extends into the cup-receiving cavity through the aperture, a first engagement feature coupled to the first portion and pivotably engaged with the first bracing feature, and a second engagement feature coupled to the first portion and engaged with the second bracing feature. The retention finger is operable to move via pivotal movement of the first engagement feature relative to the first bracing feature.