Patents by Inventor M. Celeste Simon

M. Celeste Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxygen gradient hydrogel drug screening
    Patent number: 11530381
    Abstract: The present invention describes methods for quantifying and analyzing cell migration and drug screening. Such methods include a gel (or a hydrogel) comprising a polymer, and cells that forms an oxygen gradient within the gel by controlling the balance of the diffusion of oxygen through the top of the gel and by the consumption of oxygen uptake by the cells. The migration of the cells is determined while the cells are grown in the gel of the present invention.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: December 20, 2022
    Assignees: The Johns Hopkins University, The Trustees of the University of Pennsylvania
    Inventors: Sharon Gerecht, Daniel Lewis, Kyung Min Park, T. S. Karin Eisinger, M. Celeste Simon
  • PLOD2 as a Target of Intervention for Sarcoma Metastasis
    Publication number: 20140356287
    Abstract: The invention provides compositions and methods for treating a disease or disorder by lowering the level of PLOD2 in a subject.
    Type: Application
    Filed: May 27, 2014
    Publication date: December 4, 2014
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: M. Celeste Simon, T.S. Karin Eisinger