Patents by Inventor M. Charles Liberman

M. Charles Liberman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detecting hidden hearing loss
    Patent number: 11395606
    Abstract: Non-invasive methods of detecting hidden hearing loss (cochlear synaptopathy) based on detection of an abnormal ratio of Summating Potential (SP)/Action Potential (AP) (SP/AP) Ratios.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: July 26, 2022
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: M. Charles Liberman, Stephane Maison
  • Detecting Hidden Hearing Loss
    Publication number: 20210186380
    Abstract: Non-invasive methods of detecting hidden hearing loss (cochlear synaptopathy) based on detection of an abnormal ratio of Summating Potential (SP)/Action Potential (AP) (SP/AP) Ratios.
    Type: Application
    Filed: January 20, 2017
    Publication date: June 24, 2021
    Inventors: M. Charles Liberman, Stephane Maison
  • Treating Cochlear Synaptopathy
    Publication number: 20190022101
    Abstract: Methods of treating or reducing the risk of developing hidden hearing loss by administering a small molecule Trk agonists (e.g., amitriptyline, imipramine, LM 22A4 (N,N?,N?Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide), 7, 8-dihydroxyflavone (DHF), 7,8,3?-Trihydroxyflavone (THF), Mab2256, neurotrophin-4 (NT-4), neurotrophin-3 (NT-3), brain derived neurotrophic factor (BDNF), nerve growth factor (NGF), N-acetylserotonin, N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide (HIOC), deoxygedunin, LM-22A4, or tricyclic dimeric peptide 6 (TDP6)).
    Type: Application
    Filed: January 6, 2017
    Publication date: January 24, 2019
    Applicant: Massachusetts Eye and Ear Infirmary
    Inventors: Sharon Kujawa, Albert Edge, M. Charles Liberman