Patents by Inventor M. Cristina Geroni

M. Cristina Geroni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and platinum derivatives
    Patent number: 8642580
    Abstract: Compounds which are ?-halogenoacryloyl distamycin derivatives of formula (I) wherein R1 is a bromine or chlorine atom; R2 is a distamycin or distamycin-like framework as set forth in the specification; or a pharmaceutically acceptable salt thereof; are cytotoxic agents particularly effective in the treatment of tumors over expressing GSH/GSTs system and which are poorly responsive or even resistant to conventional antitumor therapies.
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: February 4, 2014
    Assignee: Nerviano Medical Sciences S.R.L.
    Inventors: M. Cristina Geroni, Paolo Cozzi, Italo Beria
  • Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and alkylating agents
    Publication number: 20030180383
    Abstract: Compounds which are &agr;-halogenoacryloyl distamycin derivatives of formula (I) wherein R1 is a bromine or chlorine atom; R2 is a distamycin or distamycin-like framework as set forth in the specification; or a pharmaceutically acceptable salt thereof; are cytotoxic agents particularly effective in the treatment of tumors over expressing GSH/GSTs system and which are poorly responsive or even resistant to conventional antitumor therapies.
    Type: Application
    Filed: December 23, 2002
    Publication date: September 25, 2003
    Inventors: M. Cristina Geroni, Paolo Cozzi, Italo Beria