Patents by Inventor Mà del Carmen Onrubia Miguel

Mà del Carmen Onrubia Miguel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid and its trihydrated monosodium salt
    Patent number: 6573401
    Abstract: The invention relates to a process for the preparation of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid and of the trihydrated monosodium salt thereof, consisting of reacting 4-aminobutyric acid with a phosphonation mixture formed by phosphorous acid and methanesulfonic anhydride and thereafter hydrolyzing the product of said reaction and isolating the products by adjustment of the pH.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: June 3, 2003
    Assignee: Medichem, S.A.
    Inventors: Jordi Bosch i Lladó, Eugenia Pagans Lista, Ma del Carmen Onrubia Miguel
  • Process for producing gabapentin or pharmaceutical grade
    Patent number: 6528682
    Abstract: The invention describes a process for the preparation of pharmaceutical grade gabapentin, consisting of neutralizing an alcoholic solution of gabapentin hydrochloride with basic ion exchange resins and thereafter directly isolating the gabapentin, without requiring either the formation or the isolation of intermediates other than the pharmaceutical grade product.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: March 4, 2003
    Assignee: Medichem, S.A.
    Inventors: Jordi Bosch Lladó, Mà del Carmen Onrubia Miguel, Eugènia Pagans Lista