Patents by Inventor M. J. W. Visseren

M. J. W. Visseren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof
    Patent number: 5554724
    Abstract: The invention describes peptides derived from tumor rejection antigen precursor MAGE-2. These peptides bind with HLA-A2 molecules, thus presenting complexes which provoke cytolytic T cell production. The resulting "CTLs" are specific for complexes of HLA-A2 and the peptide. The complexes can be used to generate monoclonal antibodies. The cytolytic T cells produced may be used in the context of immunotherapy, such as adoptive transfer.
    Type: Grant
    Filed: March 24, 1994
    Date of Patent: September 10, 1996
    Assignee: University of Leiden
    Inventors: Cornelis J. M. Melief, M. J. W. Visseren, W. M. Kast, Pierre van der Bruggen, Thierry Boon-Falleur