Patents by Inventor MÉLANIE FLAENDER

MÉLANIE FLAENDER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250251388
    Abstract: The present invention relates to methods using trained classifier for assessing potency of a compound to revert the phenotype of a myotube exhibiting features of a neuromuscular disorder of interest into a healthy phenotype, for predicting the ability of a compound to treat a neuromuscular disorder of interest, for monitoring the response to a therapeutic compound of a patient affected with a neuromuscular disorder of interest, for selecting a patient affected with a neuromuscular disorder of interest for a treatment with a therapeutic compound or for determining whether a patient affected with a neuromuscular disorder of interest is susceptible to benefit from a treatment with a therapeutic compound, or for diagnosing a neuromuscular disorder of interest.
    Type: Application
    Filed: January 24, 2023
    Publication date: August 7, 2025
    Inventors: TIPHAINE CHAMPETIER, BEATRICE DARIMONT, MÉLANIE FLAENDER, CÉCILE GASTON, OANA LORINTIU, ANTOINE MARTIN TISSIER, PAULINE POYDENOT, LUC SELIG, ERWANN VENTRE
  • Publication number: 20250213544
    Abstract: The present invention relates to ALK5 inhibitors and their uses as skeletal muscle hypertrophy inducers as well as to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and/or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase muscle mass, muscle strength and/or muscle performance in a subject.
    Type: Application
    Filed: March 21, 2025
    Publication date: July 3, 2025
    Inventors: PAULINE POYDENOT, JORIS MICHAUD, MÉLANIE FLAENDER, EVE DUCHEMIN-PELLETIER, LUC SELIG
  • Publication number: 20210015807
    Abstract: The present invention relates to ALK5 inhibitors and their uses as skeletal muscle hypertrophy inducers as well as to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and/or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase muscle mass, muscle strength and/or muscle performance in a subject.
    Type: Application
    Filed: March 25, 2019
    Publication date: January 21, 2021
    Inventors: PAULINE POYDENOT, JORIS MICHAUD, MÉLANIE FLAENDER, EVE DUCHEMIN-PELLETIER, LUC SELIG
  • Publication number: 20200054649
    Abstract: The present invention relates to skeletal muscle hypertrophy inducers as well as their uses to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and/or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase muscle mass, muscle strength and/or muscle performance in a subject.
    Type: Application
    Filed: November 17, 2017
    Publication date: February 20, 2020
    Inventors: PAULINE POYDENOT, JORIS MICHAUD, MÉLANIE FLAENDER, EVE DUCHEMIN-PELLETIER, LUC SELIG
  • Publication number: 20200054578
    Abstract: The present invention relates to LSD/ inhibitors and their uses as skeletal muscle hypertrophy inducers as well as to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and/or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase muscle mass, muscle strength and/or muscle performance in a subject.
    Type: Application
    Filed: November 17, 2017
    Publication date: February 20, 2020
    Inventors: PAULINE POYDENOT, JORIS MICHAUD, MÉLANIE FLAENDER, EVE DUCHEMIN-PELLETIER, LUC SELIG