Patents by Inventor M. Luisa Roberts

M. Luisa Roberts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION TREATMENT FOR NON-HEMATOLOGIC MALIGNANCIES
    Publication number: 20110014207
    Abstract: The present invention relates to a therapeutic method for the treatment of non-hematologic malignancies comprising administering anti-IGF-1R antibodies, particularly human anti-IGF-1R antibodies, to a patient, in conjunction with the administration of at least one other therapeutic agent. The invention further relates to pharmaceutical compositions comprising these antibodies and methods of using such compositions thereof for treatment.
    Type: Application
    Filed: September 25, 2009
    Publication date: January 20, 2011
    Inventors: Antonio Gualberto, Bruce D. Cohen, Carrie L. Melvin, M. Luisa Roberts
  • Combination treatment for non-hematologic malignancies
    Patent number: 7618626
    Abstract: The present invention relates to a therapeutic method for the treatment of non-hematologic malignancies comprising administering anti-IGF-1R antibodies, particularly human anti-IGF-1R antibodies, to a patient, in conjunction with the administration of at least one other therapeutic agent. The invention further relates to pharmaceutical compositions comprising these antibodies and methods of using such compositions thereof for treatment.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: November 17, 2009
    Assignee: Pfizer Inc
    Inventors: Antonio Gualberto, Bruce D. Cohen, Carrie L. Melvin, M. Luisa Roberts
  • Antisense modulation of human Rho family gene expression
    Publication number: 20030199467
    Abstract: This invention provides compositions and methods for modulating expression of members of the human Rho gene family, which encode low molecular weight GTPases that act as molecular switches in signal transduction. In preferred embodiments, Rho family members include RhoA, RhoB, RhoC, RhoG, Rac1 and cdc42. This invention is also directed to methods for inhibiting hyperproliferation of cells; these methods can be used diagnostically or therapeutically. Furthermore, this invention is directed to treatment of conditions associated with expression of the human Rho family members, particularly in hyperproliferative disorders.
    Type: Application
    Filed: June 21, 2002
    Publication date: October 23, 2003
    Inventors: M. Luisa Roberts, Lex M. Cowsert
  • Antisense modulation of human Rho family gene expression
    Patent number: 6410323
    Abstract: This invention provides compositions and methods for modulating expression of members of the human Rho gene family, which encode low molecular weight GTPases that act as molecular switches in signal transduction. In preferred embodiments, Rho family members include RhoA, RhoB, RhoC, RhoG, Rac1 and cdc42. This invention is also directed to methods for inhibiting hyperproliferation of cells; these methods can be used diagnostically or therapeutically. Furthermore, this invention is directed to treatment of conditions associated with expression of the human Rho family members, particularly in hyperproliferative disorders.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: June 25, 2002
    Assignee: ISIS Pharmaceuticals, Inc.
    Inventors: M. Luisa Roberts, Lex M. Cowsert