Patents by Inventor Mónica Rosa
Mónica Rosa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240100122Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: ApplicationFiled: April 19, 2023Publication date: March 28, 2024Applicant: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Bernard Francis McDonald, Monica Rosa
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Publication number: 20240091304Abstract: A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon.Type: ApplicationFiled: July 24, 2023Publication date: March 21, 2024Applicant: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Monica Rosa
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Publication number: 20230138444Abstract: The present invention relates to new stable pharmaceutical compositions containing 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid and sodium ions that are essentially free from complexing solubilizing agents, such as PEG, cyclodextrin, lysine, arginine, in particular HPBCD. The invention further relates to methods of preparation of said pharmaceutical compositions. The invention further relates to use of said pharmaceutical compositions in methods of treatment of and/or as a prophylactic for illnesses, particularly its use as an antiviral, preferably against cytomegaloviruses.Type: ApplicationFiled: March 1, 2021Publication date: May 4, 2023Applicant: AIC246 AG & Co. KGInventors: Helmut BUSCHMANN, Thomas GOLDNER, Jessica REDMER, Jordi Carles CERON BERTRAN, Andrea HAWE, Matthias LUCKE, Dorothea HOHMANN, Monica ROSA
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Publication number: 20230095980Abstract: The present invention relates to new stable pharmaceutical compositions containing sodium 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)-phenyl]-4H-quinazolin-4-yl]acetate that are essentially free of complexing solubilizing agents, such as PEG, cyclodextrin, lysin, arginine, in particular HPBCD. The invention further relates to methods of preparation of said pharmaceutical compositions. The invention further relates to use of said pharmaceutical compositions in methods of treatment of and/or as a prophylactic for illnesses, particularly its use as an antiviral, preferably against cytomegaloviruses.Type: ApplicationFiled: March 1, 2021Publication date: March 30, 2023Applicant: AIC246 AG & Co. KGInventors: Helmut BUSCHMANN, Thomas GOLDNER, Jessica REDMER, Andrea HAWE, Matthias LUCKE, Dorothea HOHMANN, Monica ROSA
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Publication number: 20220080026Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: ApplicationFiled: April 30, 2021Publication date: March 17, 2022Applicant: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Bernard Francis McDonald, Monica Rosa
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Publication number: 20210386817Abstract: A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon.Type: ApplicationFiled: January 7, 2021Publication date: December 16, 2021Applicant: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Monica Rosa
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Publication number: 20190381131Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: ApplicationFiled: July 2, 2019Publication date: December 19, 2019Applicant: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Mónica Rosa, Bernard Francis McDonald
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Patent number: 10434138Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: GrantFiled: November 7, 2014Date of Patent: October 8, 2019Assignee: Sublimity Therapeutics LimitedInventors: Ivan Coulter, Vincenzo Aversa, Mónica Rosa, Bernard Francis McDonald
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Publication number: 20180360909Abstract: A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon.Type: ApplicationFiled: August 23, 2018Publication date: December 20, 2018Applicant: Sigmoid Pharma LimitedInventors: Ivan Coulter, Vincenzo Aversa, Monica Rosa
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Publication number: 20160317609Abstract: A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon.Type: ApplicationFiled: November 7, 2014Publication date: November 3, 2016Applicant: Sigmoid Pharma LimitedInventors: Ivan Coulter, Vincenzo Aversa, Monica Rosa
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Publication number: 20160310561Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: ApplicationFiled: November 7, 2014Publication date: October 27, 2016Applicant: Sigmoid Pharma LimitedInventors: Ivan Coulter, Vincenzo Aversa, Bernard Francis McDonald, Monica Rosa
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Patent number: 9220681Abstract: This invention relates to compositions for delivering one or more active ingredients, and more particularly to compositions, e.g. beads, comprising a matrix material which matrix material comprises a microorganism. In particular, the invention relates to compositions comprising a microorganism selected from live, killed, attenuated and inactivated microorganisms. The matrix material may also comprise a surfactant and may further comprise an adjuvant. The invention further relates to the manufacture and use of such compositions, and to other subject matter.Type: GrantFiled: July 5, 2013Date of Patent: December 29, 2015Assignee: Sigmoid Pharma LimitedInventors: Ivan Coulter, Bernard Francis McDonald, Vincenzo Aversa, Mónica Rosa
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Publication number: 20150132374Abstract: A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon.Type: ApplicationFiled: November 7, 2014Publication date: May 14, 2015Applicant: SIGMOID PHARMA LIMITEDInventors: Ivan Coulter, Vincenzo Aversa, Mónica Rosa
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Publication number: 20150132396Abstract: The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations.Type: ApplicationFiled: November 7, 2014Publication date: May 14, 2015Applicant: SIGMOID PHARMA LIMITEDInventors: Ivan Coulter, Vincenzo Aversa, Mónica Rosa, Bernard Francis McDonald
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Publication number: 20140017313Abstract: This invention relates to compositions for delivering one or more active ingredients, and more particularly to compositions, e.g. beads, comprising a matrix material which matrix material comprises a microorganism. In particular, the invention relates to compositions comprising a microorganism selected from live, killed, attenuated and inactivated microorganisms. The matrix material may also comprise a surfactant and may further comprise an adjuvant. The invention further relates to the manufacture and use of such compositions, and to other subject matter.Type: ApplicationFiled: July 5, 2013Publication date: January 16, 2014Applicant: Sigmoid Pharma LimitedInventors: Ivan Coulter, Bernard Francis McDonald, Vincenzo Aversa, Mónica Rosa