Abstract: An auricular peripheral nerve field stimulator includes at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, and an electrical stimulation device electrically coupled to the at least one therapy electrode, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the percutaneously inserted at least one therapy electrode to stimulate at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined signal amplitude, a defined pulse frequency, a defined pulse width, a defined duty cycle and a defined stimulation signal duration.

Abstract: A container accessory for dispensing fluid from a container comprises a first container attachment, a body, a dispensing head, and a second container attachment. The container accessory has a fluid pathway from the first container attachment through the body to the dispensing head. Upon attaching an outlet of a container to the first container attachment, fluid may flow by gravity from the container through the fluid pathway and be dispensed by the dispensing head. Upon attaching an outlet of a container to the second attachment, fluid is prevented from flowing through the fluid pathway and is maintained within the container. Therefore, during delivery and storage of a container, the container accessory may be attached to the second attachment to prevent spilling fluid from the container.

Abstract: A potted plant turntable including a base and a rotating dish. The rotating dish supports a potted plant which may be rotated with the dish to allow more even exposure of the plant to sunlight. The dish rests on a bearing collar of the base and may be manually rotated or driven by a motor. Drainage holes are spaced from the center of the dish and for many embodiments spaced radially inwardly from an outer edge.

Abstract: Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of galectin-3 to ligands are disclosed. For example, inhibitors of galectin-3 are described and pharmaceutical compositions comprising at least one such agent are described.

Abstract: A wheelchair is provided. First supports for supporting a user of the wheelchair are unevenly disposed to form a perimeter, and second supports for supporting the user of the wheelchair are unevenly disposed at least partially within the perimeter of the first supports. The first supports support the user when the first supports are in a raised position and the second supports are in a lowered position. The second supports support the user when the second supports are in a raised position and the first supports are in a lowered position. A alternation of supporting the user with the first supports or the second supports facilitates reduction of pressure sores of the user. In various embodiments, multiple groups of supports are used, the supports contour to a user's anatomy and/or the supports are pneumatic.

Abstract: In one aspect, a method includes forming an electrical path between p-type mercury cadmium telluride and a metal layer. The forming of the electrical path includes depositing a layer of polycrystalline p-type silicon directly on to the p-type mercury cadmium telluride and forming the metal layer on the layer of polycrystalline p-type silicon. In another aspect, an apparatus includes an electrical path. The electrical path includes a p-type mercury cadmium telluride layer, a polycrystalline p-type silicon layer in direct contact with the p-type mercury cadmium telluride layer, a metal silicide in direct contact with the polycrystalline p-type silicon layer, and an electrically conductive metal on the metal silicide. In operation, holes, indicative of electrical current on the electrical path, flow from the p-type mercury cadmium telluride layer to the electrically conductive metal.

Abstract: Compounds, compositions, and methods for treating and/or preventing at least one disease, disorder, and/or condition N associated with E-selectin, galectin-3, and/or CXCR4 chemokine receptor activity are disclosed herein. For example, multimeric glycomimetic inhibitors of E-selectins, galectin-3, and/or CXCR4 chemokine receptors and their use for treating and/or preventing inflammatory diseases, fibrosis, and cancers are disclosed. Formula (I).

Abstract: Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin, galectin-3, or E-selectin and galectin-3 to ligands a disclosed. For example, heterobifunctional inhibitors of E-selectin and galectin-3 are described and pharmaceutical compositions comprising at least one such agent is described.

Abstract: Disclosed herein are bathing garments and methods for showering, for example, outdoors after outdoor activities, such as various sports, fitness competitions, or obstacle races. In one aspect, the bathing garment includes a tubular body panel having an interior surface and exterior surface, a first edge defining a first opening and second edge defining a second opening, the body panel comprising: a plurality of apertures contained within the first and second edges of the body panel, and at least one closure means configured to selectively adjust at least one opening size from a fully open position to a fully closed position. Also disclosed herein are methods for using the disclosed garments.

Abstract: Seat covers for a seat with a headrest are disclosed. The design includes a seat cover for a seat having a headrest, including a backrest cover sized to at least partially cover a backrest of the seat, an opening disposed on the backrest cover sized to allow the headrest to pass therethrough, and a flap sized to cover the opening and that is transitionable between a closed position and an open position. The opening is sized similar to the flap and the backrest cover has a securable slit provided therein. The flap in the open position and the slit in an unsecured orientation enables the seat cover to fit over the headrest, and the flap can be closed under the headrest and the securable slit secured to form a closed orientation.

Abstract: A wheelchair is provided. First supports for supporting a user of the wheelchair are unevenly disposed to form a perimeter, and second supports for supporting the user of the wheelchair are unevenly disposed at least partially within the perimeter of the first supports. The first supports support the user when the first supports are in a raised position and the second supports are in a lowered position. The second supports support the user when the second supports are in a raised position and the first supports are in a lowered position. A alternation of supporting the user with the first supports or the second supports facilitates reduction of pressure sores of the user. In various embodiments, multiple groups of supports are used, the supports contour to a user's anatomy and/or the supports are pneumatic.

Abstract: A network device is configured to associate a tenant of a plurality of tenants with a virtual routing and forwarding (VRF) instance of a plurality of VRF instances. The network device receives a packet comprising metadata specifying a tenant identifier for the tenant. The network device identifies, based on the tenant identifier specified by the metadata, the VRF instance associated with the tenant. The network device retrieves one or more routes from a routing information base (RIB) of the VRF instance associated with the tenant and forwards the packet toward a destination via the one or more routes.

Abstract: A process is provided for the synthesis of an intermediate of Formula 15 which is useful in the synthesis of E-selectin inhibitors. Also provided are useful intermediates obtained from the process.

Abstract: A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.

Abstract: An auricular nerve field stimulation device may include first non-percutaneous electrodes arranged to contact a ventral aspect of an auricle, second non-percutaneous electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first electrodes and respective ones of the second electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first electrodes and respective ones of the second electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle.

Abstract: Compounds, compositions, and methods for modulating in vitro and in vivo processes mediated by selectin binding are described herein. For example, multimeric selectin modulators and their use are described, wherein the multimeric selectin modulators comprise a glycomimetic linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).

Abstract: An auricular nerve field stimulation device may include a first plurality of electrodes arranged to contact a ventral aspect of an auricle, a second plurality of electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle.

Abstract: A potted plant turntable including a base and a rotating dish. The rotating dish supports a potted plant which may be rotated with the dish to allow more even exposure of the plant to sunlight. The dish rests on a bearing collar of the base and may be manually rotated or driven by a motor. Drainage holes are spaced from the center of the dish and for many embodiments spaced radially inwardly from an outer edge.

Abstract: Techniques are described for a router providing metric-based multi-hop path selection. For example, a first router of a plurality of routers receives a plurality of network performance metrics for a plurality of links interconnecting the plurality of routers. The plurality of links form a plurality of multi-hop paths through the plurality of routers to a service instance. The router determines, based on the plurality of network performance metrics for the plurality of links, an end-to-end performance of each of the plurality of multi-hop paths. The router selects a multi-hop path over which to forward traffic associated with the session based on the end-to-end performance of each of the plurality of multi-hop paths and one or more performance requirements for a service associated between a session between a client device and the service instance. The router forwards the traffic to the service instance along the selected multi-hop path.