Abstract: A vehicular trailer assist system includes a plurality of vehicle cameras disposed at a vehicle, a trailer camera disposed at a rear portion of a trailer and viewing at least rearward of the trailer, and an electronic control unit (ECU) having a processor operable to process image data captured by the cameras. A display screen displays images of a region rearward of the trailer and includes a touch screen. Responsive to a touch input that is representative of a target location, the ECU, via processing of image data captured by the cameras, determines a path of travel for the vehicle and trailer to follow to maneuver the vehicle and trailer toward the target location. The ECU, responsive to an input indicative of an updated target location, updates the path of travel for the vehicle and trailer to follow to maneuver the vehicle and trailer toward the updated target location.

Abstract: An anti-theft device for protecting a portable electronic device from theft or unauthorized removal in a retail environment is provided. The anti-theft device includes a shroud configured to at least partially receive and engage a portable electronic device. The anti-theft device also includes a dock configured to releasably engage the shroud. The dock is configured to engage the shroud in a locked configuration so as to prevent removal of the shroud and the portable electronic device from the dock and to disengage the shroud in an unlocked configuration so as to allow the shroud and the portable electronic device to be removed from the dock.

Abstract: A temperature-controlled irradiation system may include an outer containment and a sealed capsule disposed within the outer containment. The sealed capsule may be configured to contain a testing material within the sealed capsule. The system may further include a temperature sensor disposed within the sealed capsule. The temperature sensor may be configured to measure a temperature of the testing material. A pressure sensor may be disposed within the sealed capsule. The pressure sensor may be configured to measure an internal pressure of the sealed capsule. The system may include a heater disposed within the sealed capsule. The heater may be configured to control the temperature of the testing material. The heater may be immersed within the testing material. A gas gap is provided between the sealed capsule and the outer containment. The gas gap may be configured to control thermal conductivity between the sealed capsule and the outer containment.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages.

Abstract: The present disclosure relates to aerosol delivery devices, methods of producing such devices, and elements of such devices. In some embodiments, the present disclosure provides devices configured for vaporization of an aerosol precursor composition that is contained in a reservoir and transported to a heating element by a liquid transport element. The liquid transport element may include a porous monolith.

Abstract: A video compression method may include providing and transmitting encoder commands for sequences of one or more pixels in a video frame in a YCbCr color space from a set of hierarchal encoder commands. A particular encoder command for a particular sequence may include on of a copy command, a delta command, or a make pixel command. A copy command may indicate that the particular sequence is identical to one of a previous pixel in the video frame, a pixel located above a first pixel of the particular sequence in the video frame, or a pixel in a previous video frame at a location of the first pixel. A delta command may indicate that the particular sequence includes a single pixel with color values equal to the previous pixel in the video frame combined with a signed color delta. A make pixel command may provide color values of particular sequence.

Abstract: The present disclosure provides SEZ6 antibody drug conjugates (ADCs), including compositions and methods of using such ADCs.

Abstract: Redo logs are used to facilitate efficient cloning of virtual machines. When a virtual machine with a virtual hard disk is to be cloned, two redo logs are created, both of which are linked to the virtual hard disk. The virtual machine being cloned is then linked to one redo log, and a newly created virtual machine is linked to the other. Each time an additional virtual machine is created, two new redo logs are created and linked to the end of the disk chain. The parent and newly created virtual machine are each linked to one of the new redo logs.

Abstract: The disclosure provides crystalline forms for certain synthetic intermediates for making belzutifan, a HIF-2? inhibitor, useful for the treatment of cancer. The disclosure also provides processes for isolating the crystalline forms.

Abstract: A vehicular vision system includes an underbody camera disposed at an underside of a body of a vehicle and viewing a ground surface under the body of the vehicle and being traveled on by the vehicle. The underbody camera captures image data as the vehicle is moving, An illumination source, when operated to emit light, emits near infrared light illuminating the ground surface under the body of the vehicle. An electronic control unit (ECU) is disposed at the vehicle and includes an image processor that processes image data captured by the underbody camera. The underbody camera views at least forward towards a front portion of the underside of the body of the vehicle. The vehicular vision system, via processing at the ECU of image data captured by the underbody camera, determines presence of an object forward of the underbody camera and having height greater than a threshold height.

Abstract: The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2?-(S)-fluoro-thio-adenosine monophosphate or 2?-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

Abstract: A rapidly-orodispersible dosage form comprising a porous, bound-powder matrix and one or more internal cavities is provided, as well as three-dimensional printing methods for making the same. Each internal cavity is configured to contain one or more payloads, particularly pharmaceutical medicaments, while isolating the payloads from the external environment outside of the dosage form. Each payload can be contained within its cavity in its native form without having to be combined with the bound-powder matrix or binding liquid. Dosage forms can disintegrate in water or saliva in less than two minutes, independently of the payload(s) or medicament(s) contained within. The dosage forms can be formed as unitary tablets, or as two-piece tablets comprising a container body and a lidding body that are secured together to isolate the one or more cavities and their payloads inside.

Abstract: Bone implants, including methods of use and assembly. The bone implants, which are optionally composite implants, generally include a distal anchoring region and a growth region that is proximal to the distal anchoring region. The distal anchoring region can have one or more distal surface features that adapt the distal anchoring region for anchoring into iliac bone. The growth region can have one or more growth features that adapt the growth region to facilitate at least one of bony on-growth, in-growth, or through-growth. The implants may be positioned along a posterior sacral alar-iliac (“SAT”) trajectory. The implants may be coupled to one or more bone stabilizing constructs, such as rod elements thereof.

Abstract: Components resolved in time by a thermal desorption separator accumulate in a sample cell and are analyzed by electromagnetic radiation-based spectroscopic techniques.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages.

Abstract: A vehicular trailer guidance system includes an electronic control unit (ECU), a rear backup camera and a trailer camera disposed at a rear portion of a trailer hitched to the vehicle. A display screen is disposed in the vehicle and viewable by a driver of the vehicle. With the trailer hitched to the vehicle, the display screen is operable to display video images derived from image data captured by the trailer camera. At least in part via processing at the ECU of image data captured by the trailer camera, an instruction that aids maneuvering the vehicle in reverse with the trailer hitched thereto during a reversing maneuver of the vehicle and trailer is generated. During the reversing maneuver of the vehicle and trailer, the display screen displays an alert when angling of the trailer relative to the vehicle approaches a jackknife condition.

Abstract: A method and system of forming a pharmaceutical dosage form within a portion of a blister packaging. The method includes the steps of providing a blister packaging for the dosage form with depressions. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially uniform powder layer within the depressions. A binding liquid is then deposited in a pattern on the powder layer within the depressions, to bind the particles of the powder layer and form an incremental wetted powder layer. Excess solvent in the binding material can be removed to form an incremental bound layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister packaging.

Abstract: Bone implants, including methods of use and assembly. The bone implants, which are optionally composite implants, generally include a distal anchoring region and a growth region that is proximal to the distal anchoring region. The distal anchoring region can have one or more distal surface features that adapt the distal anchoring region for anchoring into iliac bone. The growth region can have one or more growth features that adapt the growth region to facilitate at least one of bony on-growth, in-growth, or through-growth. The implants may be positioned along a posterior sacral alar-iliac (“SAI”) trajectory. The implants may be coupled to one or more bone stabilizing constructs, such as rod elements thereof.

Abstract: The present disclosure describes various embodiments of systems, apparatuses, and methods for large-scale processing of weather-related data. For one such system, the system comprises a database of weather-related data providing from at least one weather monitoring station and at least one processor for coordinating a data processing job for processing a set of input weather-related data from the database. Accordingly, the input data comprises sensor data from the at least one weather monitoring station positioned on an open shoreline during a hydrodynamic event, weather model data for the hydrodynamic event, and at least one of air-craft reconnaissance data or satellite reconnaissance data regarding the hydrodynamic event, wherein the at least one processor is configured to assimilate the input data and generate, using machine learning, an improved weather prediction model for the hydrodynamic event. Other systems, apparatuses, and methods are also provided.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages, including automatically closing a container filled with the packages.