Patents by Inventor Mária Mareková

Mária Mareková has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-Invasive Successfulness Test of In Vitro Fertilization Process
    Publication number: 20260258497
    Abstract: A non-invasive successfulness test of in vitro fertilization process includes two independent steps: the step of identification and analysis of the prognostic canonical and iso-miRNA biomarkers from women's peripheral blood plasma on the day of the IVF process—the Success Test; and the step of prognostic canonical miRNA and iso-miRNA biomarkers from a spent blastocyst medium collected once on day 4 to 6 of the embryo's cultivation—the CultMed Test; wherein the successful Success Test shows the cut off values of the selected miRNA biomarkers at reads number of 1 being ?1, and the cut off value of miRNA iso-hsa-let-7b-5p_TGAGGTAGTATGTTGTGTGG at reads number of 5 being ?5, and the successful CultMed Test shows the cut off value of the selected miRNA biomarkers at reads number of 1 being ?1; and wherein the values in both tests predict the successful in vitro fertilization process.
    Type: Application
    Filed: October 22, 2025
    Publication date: September 3, 2026
    Inventors: Miroslava Rabajdová, Ondrej Slabý, Katarína Šoltys, Mária Mareková, Silvia Toporcerová
  • Non-Invasive Successfulness Test of In Vitro Fertilization Process
    Publication number: 20230257809
    Abstract: It includes two independent steps: the step of identification and analysis of the prognostic canonical and iso-miRNA biomarkers from women's peripheral blood plasma on the day of the IVF process—the Success Test; and the step of prognostic canonical miRNA and iso-miRNA biomarkers from a spent blastocyst medium collected once on day 4 to 6 of the embryo's cultivation—the CultMed Test; wherein the successful Success Test shows the cut off values of the selected miRNA biomarkers at reads number of 1 being ?1, and the cut off value of miRNA iso-hsa-let-7b-5p_TGAGGTAGTATGTTGTGTGG at reads number of 5 being ?5, and the successful CultMed Test shows the cut off value of the selected miRNA biomarkers at reads number of 1 being ?1; and wherein the values in both tests predict the successful in vitro fertilization process.
    Type: Application
    Filed: March 1, 2021
    Publication date: August 17, 2023
    Inventors: Miroslava Rabajdová, Ondrej Slabý, Katarína Soltys, Mária Mareková, Silvia Toporcerová