Patents by Inventor M. Ross Bullock

M. Ross Bullock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230349929
    Abstract: The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the severity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilitation efforts, and monitor response to treatment for a patient with a central nervous system injury are also described.
    Type: Application
    Filed: July 5, 2023
    Publication date: November 2, 2023
    Inventors: Robert W. KEANE, W. Dalton DIETRICH, Juan Pablo DE RIVERO VACCARI, Stephanie ADAMCZAK, M. Ross BULLOCK, Allan LEVI, Michael Y. WANG
  • Publication number: 20200363432
    Abstract: The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the severity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilitation efforts, and monitor response to treatment for a patient with a central nervous system injury are also described.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 19, 2020
    Inventors: Robert W. KEANE, W. Dalton DIETRICH, Juan Pablo DE RIVERO VACCARI, Stephanie ADAMCZAK, M. Ross BULLOCK, Allan LEVI, Michael Y. WANG
  • Publication number: 20170003303
    Abstract: The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the serverity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilition efforts, and monitor response to treatment for a patient with a central nervous system injury are also described.
    Type: Application
    Filed: July 20, 2016
    Publication date: January 5, 2017
    Inventors: Robert W. Keane, W. Dalton Dietrich, Juan Pablo de Rivero Vaccari, Stephanie Adamczak, M. Ross Bullock, Allan Levi, Michael Y. Wang
  • Publication number: 20150185232
    Abstract: The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the severity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilitation efforts, and monitor response to treatment for a patient with a central nervous system injury are also described.
    Type: Application
    Filed: February 6, 2013
    Publication date: July 2, 2015
    Inventors: Robert W. Keane, W. Dalton Dietrich, Juan Pablo de Rivero Vaccari, Stephanie Adamczak, M. Ross Bullock, Allan Levi, Michael Y. Wang
  • Patent number: 8404752
    Abstract: This invention provides for methods of treating a subject suffering from central nervous system injury, including traumatic brain injury, comprising administering to the subject an amount of a perfluorocarbon. This invention also provides for use of a perfluorocarbon in the manufacture of a medicament for treating a subject suffering from central nervous system injury including traumatic brain injury. This invention further provides for a pharmaceutical composition comprising a perfluorocarbon for use in treating a subject suffering from central nervous system injury, including traumatic brain injury.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: March 26, 2013
    Assignees: Oxygen Biotherapeutics, Inc., Virginia Commonwealth University
    Inventors: M. Ross Bullock, Bruce Spiess, Deborah P. Thompson
  • Publication number: 20100178347
    Abstract: This invention provides for methods of treating a subject suffering from central nervous system injury, including traumatic brain injury, comprising administering to the subject an amount of a perfluorocarbon. This invention also provides for use of a perfluorocarbon in the manufacture of a medicament for treating a subject suffering from central nervous system injury including traumatic brain injury. This invention further provides for a pharmaceutical composition comprising a perfluorocarbon for use in treating a subject suffering from central nervous system injury, including traumatic brain injury.
    Type: Application
    Filed: July 17, 2009
    Publication date: July 15, 2010
    Inventors: M. Ross Bullock, Bruce Spiess, Deborah P. Thompson